research Management of Androgenetic Alopecia
Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.
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research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
Method detects finasteride in plasma at very low concentrations.
research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments
Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
research The Biology of Hair Diversity
Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.
research Treatment Strategies for Alopecia
Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
research Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome
The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
research Safety Concerns When Using Novel Medications to Treat Alopecia
Consider benefits and risks of new alopecia treatments for safety.
research Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia
Dutasteride is safe and effective for treating hair loss, but may decrease libido.
research Finasteride and Androgenic Alopecia: From Therapeutic Options to Medical Implications
Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
research Are 2D:4D Finger-Length Ratios an Indicator of Androgenetic Alopecia in Males?
Right hand finger ratio may predict male hair loss.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Serenoa Repens and N-Acetyl Glucosamine/Milk Proteins Complex Differentially Affect the Paracrine Communication Between Endothelial and Follicle Dermal Papilla Cells
Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
research Telogen Effluvium: Comprehensive Overview and Treatment
Telogen Effluvium is a hair loss condition where treatment involves identifying and managing its triggers.
research Pharmacological and Phytochemical Updates on Citrullus Colocynthis and Citrullus Lanatus
Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.
research Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production
Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
research Molecular Basis of Androgenetic Alopecia
research Stauntonia Hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-Induced Alopecia Mice
Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
research Effect of Dutasteride on the Detection of Prostate Cancer in Men with Benign Prostatic Hyperplasia
Dutasteride may lower the chance of finding prostate cancer in men with enlarged prostates.
research Effects of In Utero Exposure to Finasteride on Androgen-Dependent Reproductive Development in Male Rats
Exposure to finasteride in the womb caused lasting reproductive issues in male rats.
research Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands
New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.
research Saw Palmetto
Saw palmetto can help with prostate issues and may promote hair growth.
research 5-Alpha Reductase Deficiency
5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research 5α-Reductase Inhibitors: Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research The Role of Non-Aromatizable Testosterone Metabolite in Metabolic Pathways
Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.
research Incidence of Serious Infectious Events with Methotrexate Treatment: Meta-Analysis of Randomized Controlled Trials
Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.
research Design, Synthesis, and Biological Evaluation of Novel Androst-3,5-Diene-3-Carboxylic Acid Derivatives as Inhibitors of 5α-Reductase Type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research Finasteride Monotherapy Before TURP: Significant Improvement in Early Postoperative Quality of Life
Finasteride before TURP reduces blood loss and improves early postoperative quality of life.
research What Do We Know About 5-Alpha Reductase Inhibitors?
Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.