Search
for
Sort by
Research
360-390 / 1000+ resultsresearch Cosmeceutical Potentials of Equisetum Debile Roxb. Ex Vaucher Extracts
![Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia](/images/research/f8c40e2f-1ed6-41a2-aeed-aa4682dcce13/small/15223.jpg)
research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
![Novel Inhibitors of 5α-Reductase](/images/research/ff6a59d6-b298-4437-8735-b49febe727b7/small/20479.jpg)
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
![Crystal Structure of Steroid Reductase SRD5A Reveals Conserved Steroid Reduction Mechanism](/images/research/20f9c984-a193-4adc-b3cb-9811a6ade073/small/31784.jpg)
research Crystal Structure of Steroid Reductase SRD5A Reveals Conserved Steroid Reduction Mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
![Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice](/images/research/f66aa477-6993-472c-a555-4feb295267ee/small/2743.jpg)
research Sex Differences in the Effect of Finasteride on Acute Ethanol Withdrawal Severity in C57BL/6J and DBA/2J Mice
Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.
![5α-Reductases in Human Physiology: An Unfolding Story](/images/research/6a65600c-6416-41eb-9e39-2cc026dfc669/small/14635.jpg)
research 5α-Reductases in Human Physiology: An Unfolding Story
We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.
![5α-Reductases in Human Physiology: An Unfolding Story](/images/research/746bae71-c929-4ff5-a2d7-142ec295d02c/small/14697.jpg)
research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
![Hair Growth Promotant Activity of Petroleum Ether Root Extract of Glycyrrhiza Glabra L (Fabaceae) in Female Rats](/images/research/b5e96503-7371-49aa-8738-d78fb76896ac/small/23128.jpg)
research Hair Growth Promotant Activity of Petroleum Ether Root Extract of Glycyrrhiza Glabra L (Fabaceae) in Female Rats
Licorice root extract may promote hair growth in female rats.
![Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride](/images/research/fa3cdf0c-c7b7-4025-9d4e-121a4258f109/small/4968.jpg)
research Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride
Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
![Optimization of Finasteride Nano-Emulsion Preparation Using Chemometric Approach](/images/research/14a706c2-e102-4a4f-93fc-8a6a067cec25/small/3346.jpg)
research Optimization of Finasteride Nano-Emulsion Preparation Using Chemometric Approach
Finasteride nano-emulsion optimized using chemometric approach.
![Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26](/images/research/ae79d90f-a6ee-4913-9b76-90f760f64233/small/2791.jpg)
research Genome-Wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26
Hair loss gene found on chromosome 3q26.
![Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study](/images/research/db0e4faf-02b4-4dad-9345-14338f00bbac/small/3837.jpg)
research Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study
Optimized film improves finasteride skin absorption and treatment efficiency.
![Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3](/images/research/6b33e427-b58c-4492-89cd-9f4b56211cb8/small/14839.jpg)
research Curcumin Derivatives Inhibit Testicular 17β-Hydroxysteroid Dehydrogenase 3
Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.
![TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model](/images/research/d8b49375-373d-4879-a217-68b4aaa6712e/small/13986.jpg)
research TSPO Activation Modulates the Effects of High Pressure in a Rat Ex Vivo Glaucoma Model
Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.
![A Rapid, Simple, Specific Liquid Chromatographic–Electrospray Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study](/images/research/5a1c06af-202d-479f-ad21-7edd15043675/small/2723.jpg)
research A Rapid, Simple, Specific Liquid Chromatographic–Electrospray Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study
Method measures finasteride in plasma, suitable for pharmacokinetic studies.
![Origanum Vulgare L. Leaves Extract Alleviates Testis And Sperm Damages Induced By Finasteride: Biochemical, Immunohistological And Apoptosis Genes Based Evidences](/images/research/da255e3d-51ff-4ea0-88a9-bd270fe48683/small/4944.jpg)
research Origanum Vulgare L. Leaves Extract Alleviates Testis And Sperm Damages Induced By Finasteride: Biochemical, Immunohistological And Apoptosis Genes Based Evidences
Oregano extract helps fix testis and sperm damage caused by finasteride.
![Polycystic Ovarian Syndrome: Correlation Between Hyperandrogenism, Insulin Resistance, and Obesity](/images/research/b8f68cce-3815-409e-a8f6-f9299e84e828/small/17502.jpg)
research Polycystic Ovarian Syndrome: Correlation Between Hyperandrogenism, Insulin Resistance, and Obesity
High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.
![Endocrine Disorders in Woodhouse-Sakati Syndrome: A Systematic Review of the Literature](/images/research/e7614304-0a0a-4d6a-ac27-bd9e43c23033/small/30325.jpg)
research Endocrine Disorders in Woodhouse-Sakati Syndrome: A Systematic Review of the Literature
Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.
![The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance](/images/research/03bea365-6a27-4f88-bb72-81525f07f972/small/4412.jpg)
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
![Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats](/images/research/04afab37-c7f8-45bb-89b4-a35040d3469a/small/13439.jpg)
research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
![Foundations of Bayesian Networks](/images/research/70814e37-568a-4d86-bec3-4f00c3b08291/small/20382.jpg)
research Foundations of Bayesian Networks
Bayesian networks are tools for modeling variables' probabilistic relationships, which can efficiently represent complex probabilities and help in making inferences.
![The Epidemiology of Hospital-Treated Alopecia Areata in Denmark, 1995–2016](/images/research/33d6a185-e45c-4b19-b707-6f75ae7fe50a/small/33894.jpg)
research The Epidemiology of Hospital-Treated Alopecia Areata in Denmark, 1995–2016
In Denmark from 1995 to 2016, hospital-treated alopecia areata cases increased, mostly affecting women and those over 50.
![RP-HPLC Technique for Dutasteride Quantitative Estimation in Tablet Dosage Form: Formulation and Validation of Analytical Technique](/images/research/0beeb529-d763-4b7f-a2a0-49dad362b961/small/36082.jpg)
research RP-HPLC Technique for Dutasteride Quantitative Estimation in Tablet Dosage Form: Formulation and Validation of Analytical Technique
A reliable method was developed to measure dutasteride in tablets accurately and consistently.
![The Potential Involvement of Cholinergic System in Finasteride Induced Cognitive Dysfunction](/images/research/705ba504-feb5-4e16-872e-6cbc1cb62614/small/5116.jpg)
research The Potential Involvement of Cholinergic System in Finasteride Induced Cognitive Dysfunction
Finasteride might affect memory by impacting cholinergic system.
research Vaginal Bleeding in Pre-Pubertal Females
Recurrent vaginal bleeding in young girls without puberty signs may require a genital exam to find hidden causes.
![Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production](/images/research/c39a9ec8-89ef-425c-950e-df43724e46d4/small/26816.jpg)
research Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production
Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
![The Role of 5-Alpha-Reductase Inhibition in Suppressing Progression of Male Androgenetic Alopecia and the Potential Application of Saw Palmetto Extracts](/images/research/501f5561-375c-4fe7-8321-06ec8c88358a/small/16444.jpg)
research The Role of 5-Alpha-Reductase Inhibition in Suppressing Progression of Male Androgenetic Alopecia and the Potential Application of Saw Palmetto Extracts
Saw palmetto extracts might help treat male hair loss and need more research.
![Isolation and HPLC Quantitative Determination of 5α-Reductase Inhibitors from Tectona Grandis Leaf Extract](/images/research/7a9a286c-1e15-4fef-80d7-1940e6a07d2a/small/20704.jpg)
research Isolation and HPLC Quantitative Determination of 5α-Reductase Inhibitors from Tectona Grandis Leaf Extract
Teak leaf extract contains compounds that could help treat hair loss.
research Vitamin A in Skin and Hair: An Update
Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.