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A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Women with androgenetic alopecia have normal levels of most blood steroids and binding proteins, but higher dehydroepiandrosterone. Some also have low "sex hormone-binding globulin" and "corticosteroide-binding globulin" capacity, and high "free androgen index" and "free cortisol index". Diane treatment can normalize these levels and improve hair conditions.

Removing part of the vitamin D receptor stops vitamin D from working properly.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Steroid-binding globulins have important roles beyond just transporting steroids.

GRHL3 is important for controlling gene activity in skin cells during different stages of their development.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Certain transporters are found in human hair follicles and may affect hair growth and loss.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

Certain small molecules and polymers can change hair's physical properties and how it feels by affecting the bonds within the hair.

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

People with alopecia areata have higher levels of RBP4 protein and antibodies against it.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.

Hair increases in size when it absorbs water, and treatments like bleaching affect how much water it can take in.

Nerve growth factor helps cashmere goat hair cells grow by activating a specific protein.

Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.