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The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.