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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.

The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.

JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Licorice has many health benefits but should be used carefully due to possible side effects.

No single treatment is clearly effective for central serous chorioretinopathy.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.

Human hair proteins vary by individual, body site, and ethnicity, useful for forensics.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

D'orenone stops root hair growth by disrupting auxin transport, but adding auxin can reverse this.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.