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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Skin doctors should recognize and treat conditions like hair-pulling and skin-picking early, often using therapy and medication, to help 50-70% of patients.

Trichotillomania treatment is most successful with a mix of behavioral therapy, medication, and social support.

Treating both the mind and skin together, especially by managing stress, can greatly improve outcomes for skin disorders linked to psychological issues.

Most dogs have hair whorls on their chest and limbs, with shelter dogs and short-haired dogs having more chest whorls.

The healthcare for transgender veterans could be better with a more unified team approach.

Most types of hair loss can regrow naturally, but there are no effective cures for male pattern or age-related hair loss, and only limited options for females.

A person with Turner Syndrome showed severe schizophrenia that didn't respond to treatment and had brain shrinkage.

Using too much topical minoxidil can cause serious side effects like dizziness and low blood pressure.

Effective treatments for trichotillomania include cognitive-behavioral therapy, certain medications, and alternative support tools.

Dianabol boosts muscle growth but has serious health risks and legal issues.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

The conclusion is that using the 5W1H method can improve diagnosis and management of childhood hair-pulling disorder.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

The conclusion is that self-concept, shame, and emotion regulation are key factors in hoarding disorder, body dysmorphic disorder, and trichotillomania, and should be targeted in treatment and research.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.

Trichotillomania is a challenging-to-treat impulse-control disorder where individuals pull out their hair, more common in females, with some treatments showing benefits.

Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.

Adding aripiprazole to the treatment improved hair-pulling symptoms in a teenager.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Microsechium helleri extract has antioxidant, anti-inflammatory, antidiabetic, and heart-protective benefits.

Different treatments are effective for hair loss conditions, but results vary by individual factors.

Up to half of adult women may experience hair loss, and doctors should use medical history, exams, and tests to find the cause and treat it.

Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.