29 citations
,
September 2012 in “Birth Defects Research” This review discusses the developmental regulation of wound healing mechanisms in mammals, focusing on the role of the Wnt and TGF‐β signaling pathways, and reports no new clinical findings.
Keratin could help create enamel-regenerating toothpaste in a few years.
This study utilized the USFDA AERS to identify significant associations between various medications—such as anti-osteoporotic drugs and phenytoin—and gingival disorders, noting emergent signals with finasteride, COVID-19 vaccine, and levothyroxine, suggesting a need for awareness of oral side effects.
This study identified that transgender patients face barriers in accessing oral healthcare, including discrimination and harassment, leading to increased stress, poorer oral health, and a diminished quality of life related to oral health.
26 citations
,
September 2018 in “Colloids and Surfaces B: Biointerfaces” This study reported that a novel liposomal formulation, SP-bFGF-SF-LIP, enhanced bFGF stability and skin permeability, significantly improving hair follicle recovery and wound healing in a mouse model.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.
45 citations
,
August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
37 citations
,
December 2022 in “Acta Pharmaceutica Sinica B” This review discusses the strategies and potential of CRISPR delivery for gene therapy, highlighting the challenges and innovative use of stimuli-responsive nanocarriers, but reports no new experimental results.
25 citations
,
July 2015 in “Colloids and Surfaces B: Biointerfaces” This study found that microencapsulation combined with iontophoresis can significantly enhance the delivery of minoxidil sulphate to hair follicles, suggesting a synergetic approach for topical drug targeting.
4 citations
,
January 2025 in “Journal of Materials Chemistry B” In this study, researchers developed a multifunctional, injectable hydrogel that adapts to irregularly shaped wounds, enhances healing, and shows potential antibacterial activity without significant toxicity, suggesting promise for treating chronic wounds.
9 citations
,
September 2018 in “Journal of Photochemistry and Photobiology B-biology” This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.
330 citations
,
December 2009 in “Cell stem cell” This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.
238 citations
,
March 2013 in “Development” This study found that adipocytes play a crucial role in skin wound healing by facilitating fibroblast recruitment and dermal reconstruction during the healing process.
141 citations
,
November 2005 in “International journal of pharmaceutics” This review examines the role of hair follicles and sebaceous glands in percutaneous drug delivery but does not report new clinical results; it calls for further exploration of follicle-targeting therapies.
46 citations
,
January 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Insig deficiency in the skin of mice causes cholesterol precursors to accumulate, leading to defective hair development and skin abnormalities, which were alleviated by simvastatin treatment.
10 citations
,
January 2019 in “Indian Journal of Dermatology” This study found that male patients with early-onset androgenetic alopecia were associated with metabolic syndrome, but not insulin resistance, compared to age-matched controls.
4 citations
,
December 2013 in “Veterinární medicína” In this report, two Persian cats and their owner with low immunity due to chemotherapy were identified with a rare dermatophytic infection caused by Chrysosporium spp., and the infection improved following fluconazole treatment.
March 2018 in “Cambridge University Press eBooks” Transplant patients face higher skin cancer risks due to immunosuppressive therapy, requiring careful skin health monitoring.
January 2017 in “IP Indian journal of clinical and experimental dermatology” This study found that metabolic syndrome was significantly more common in men with early-onset androgenetic alopecia compared to controls, indicating a potential increased risk of cardiovascular issues in this population.
November 2020 in “Psychoneuroendocrinology” In this study, repeated finasteride administration was associated with decreased social interaction and cognitive deficits in male rats, potentially linked to changes in cholinergic system activity.
121 citations
,
May 2009 in “Journal of Ethnopharmacology” This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.
100 citations
,
September 1999 in “British Journal of Dermatology” This study suggests that finasteride's effect on promoting hair growth in men with androgenetic alopecia may be due to its inhibition of 5aR2 localized in hair follicles.
79 citations
,
January 1982 in “The American Journal of Medicine” This study reports that VP-16-213 (etoposide) shows significant therapeutic activity in several cancers including small cell bronchogenic carcinoma and certain leukemias, with hematologic toxicity being the primary side effect.
15 citations
,
December 2011 in “Journal of the European Academy of Dermatology and Venereology” In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.
14 citations
,
August 2024 in “Breast Cancer Research and Treatment” This study found that oral minoxidil improved hair density in women experiencing late alopecia due to chemotherapy and/or endocrine therapy, with 74% showing clinical improvement and statistically significant increases in hair shaft density reported in those assessed with trichoscopy.
12 citations
,
August 2011 in “European Journal of Endocrinology” This study found that anti-Müllerian hormone (AMH) is a valuable primary variable for classifying functional androgenization, especially in distinguishing ovarian-related groups, and supports the novel stratification system.
11 citations
,
September 1992 in “Journal of pineal research” This study found that repeated immunization against melatonin in Australian feral goats temporarily increased cashmere production and altered growth cycles, but these effects diminished after the first year.
7 citations
,
April 2013 in “Clinical and Experimental Dermatology” This study found that tianeptine may suppress the transition to catagen, promoting hair growth in a stress-induced alopecia areata mouse model.
3 citations
,
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that skin pigmentation alterations in a mouse model of Carney complex may be caused by specific dermal fibroblasts promoting melanogenic signaling.
2 citations
,
January 2000 in “Elsevier eBooks” The document explains how hair is studied in forensics to identify its source and its role in criminal investigations.