January 2025 in “Medical Research Archives” This review discusses various applications of low level laser therapy and argues for a holistic evaluation of patients but reports no new clinical findings.
June 2023 in “Research Square (Research Square)” In this study, utilizing a mixture of crushed sky fruit seeds and sodium salt for goat skin preservation led to a significant reduction in environmental impact, decreasing total dissolved solids by 59% and chloride content by 44%, while maintaining the physical quality of processed leather.
27 citations
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December 2013 in “Endocrinology” This study established a mouse model for Cushing's syndrome due to a specific Crh mutation, which may help explore the effects of glucocorticoid excess and evaluate treatments for corticosteroid-induced osteoporosis.
20 citations
,
February 2017 in “International Journal of Dermatology” This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.
61 citations
,
May 2014 in “International journal of pharmaceutics” This research describes a process for producing caffeine nanocrystals, which may enhance skin penetration by accumulating in hair follicles and maintaining stability for two months, paving the way for in vivo testing.
59 citations
,
April 2016 in “Breast Cancer Research and Treatment” This study found that AR/VDR-targeted agonist hormone therapy can inhibit cell viability in HR2-av triple-negative breast cancer cell lines through multiple mechanisms and may enhance the effects of chemotherapy.
42 citations
,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” This study established a stable formulation for caffeine nanocrystals in specific solvent mixtures, which could be used to test their potential for enhanced hair follicle targeting and penetration.
39 citations
,
November 2015 in “Nanomedicine” This study found that the developed Finasteride-loaded SMEDDS improved the relative bioavailability of the drug compared to a commercial tablet, offering a promising oral delivery system for glucosteroid analogs.
18 citations
,
February 2025 in “Drug Delivery and Translational Research” This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.
18 citations
,
August 2018 in “The FASEB journal” This study found that Hoxc13-/- rabbits exhibit complete hair loss on the head and dorsum, providing a potential model for understanding human ECTD-9 and related dermatological conditions.
8 citations
,
January 2021 in “Pharmaceutics” This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.
7 citations
,
February 2019 in “Journal of Molecular Liquids” This study assessed minoxidil solubility in propylene glycol and water mixtures, comparing cosolvency models and examining thermodynamic properties, without reporting new clinical results.
4 citations
,
January 2013 in “Dissolution Technologies” This study optimized and validated a dissolution test method for immediate-release finasteride capsules, highlighting the need for an official standard due to variability in commercial products.
3 citations
,
November 2022 in “Advances in Clinical and Experimental Medicine” The authors reported that electrochemotherapy and electroporation-based treatments, both with and without cytotoxic drugs, show promise as safer and more effective options for breast cancer treatment, including metastatic cases and palliative care, in vitro and in vivo.
3 citations
,
February 2019 in “The European Research Journal” In this study, self-esteem, body image, and sexual function in women significantly improved after total laser pubic hair removal.
2 citations
,
November 2024 in “AAPS PharmSciTech” In this study, researchers found that niosomes, bilosomes, and spanlastic formulations can enhance the oral anticoagulation efficiency of rivaroxaban in rats, with spanlastic ranked as the most effective in prolonging clotting, prothrombin, and tail bleeding times compared to unprocessed rivaroxaban.
March 2026 in “Buletin Veteriner Udayana” This case report described a Persian cat with psychogenic alopecia and secondary dermatitis linked to environmental stress, which improved with antihistamine therapy, diet changes, and owner interaction, but relapsed in a high cat population setting.
November 2025 in “Jurnal Pendidikan Indonesia” In this study at the IPB Taman Kencana campus, researchers found that all examined stray cats were infested with ectoparasites, primarily Ctenocephalides felis fleas, leading to health issues such as anemia and stress.
This study developed a topical dutasteride-loaded Insitu-emulgel for treating androgenetic alopecia, finding it effectively controls drug release, enhances skin penetration, and may improve patient compliance compared to traditional topical treatments, though further clinical research is underway.
April 2021 in “European journal of medical and health sciences” This study observed an increase in alopecia cases among patients recovering from COVID-19 in Bangladesh during the pandemic compared to the previous year.
May 2018 in “Cell stem cell” This study reports that myoepithelial cells in submucosal glands can act as reserve stem cells, regenerating surface airway epithelium after severe injury through a mechanism involving Sox9 and Wnt signaling.
83 citations
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June 2020 in “Materials & Design” In this study, ACF sponges with 10% fucoidan significantly promoted wound healing and hair follicle regeneration in rats, showing improved hemostatic and antibacterial performance compared to other formulations.
326 citations
,
February 2009 in “The American journal of pathology” This review discusses the role of Lgr5 as a marker for identifying adult stem cells, particularly in the intestine and hair follicles, and reports no clinical results.
202 citations
,
August 2017 in “Nature cell biology” This study found that glycolytic metabolism and lactate production are crucial for hair follicle stem cell activation, and manipulating these processes can stimulate the hair cycle.
145 citations
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November 2018 in “Nature Communications” This study found that activating the Sonic hedgehog pathway in scarring wounds can remodel the dermis to promote hair follicle regeneration, highlighting a potential new approach to enhance healing.
130 citations
,
August 2020 in “Drug Design Development and Therapy” This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.
104 citations
,
October 2016 in “PLoS ONE” This study found that CRISPR/Cas9-mediated disruption of the FGF5 gene in goats increased hair follicle numbers and fiber length, suggesting more cashmere production could be achieved.
89 citations
,
November 2014 in “International Journal of Nanomedicine” This study suggests that spironolactone-loaded nanostructured lipid carriers could enhance follicular delivery and offer a more localized treatment for androgenic alopecia, potentially reducing systemic side effects.
88 citations
,
February 2008 in “Journal of Medicinal Chemistry” Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
86 citations
,
January 2019 in “Frontiers in Immunology” The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.