research Cyclooxygenases in the Skin: Pharmacological and Toxicological Implications
Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
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research Cell Death in the Skin: Mechanisms and Implications
Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
research Bone vs. Fat: Embryonic Origin of Progenitors Determines Response to Androgen in Adipocytes and Osteoblasts
Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
research Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics
Tiny natural vesicles from cells might help treat hair loss.
research Cystine-Thiamin-Containing Hair-Growth Formulation Modulates the Response to UV Radiation in an In Vitro Model for Growth-Limiting Conditions of Human Keratinocytes
A hair-growth formula with cystine and thiamin helps protect skin cells against UV damage and improves their growth.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Cicatricial Alopecia: What's New in Etiology?
Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
research Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice
Finasteride reduces new brain cells in male mice, possibly causing depression.
research The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
research Neuroactive Gonadal Drugs for Neuroprotection in Male and Female Models of Parkinson's Disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.
research Pathobiology of Chemotherapy-Induced Hair Loss
Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
research LncRNA MTC Enhances the Proliferation of Liaoning Cashmere Goat Skin Fibroblasts by Modulating GSTM1-ASK1 Interaction
LncRNA MTC boosts growth of goat skin cells, improving cashmere quality.
research Stress-Sensing in the Human Greying Hair Follicle: Ataxia Telangiectasia Mutated (ATM) Depletion in Hair Bulb Melanocytes in Canities-Prone Scalp
Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Revolutionizing Radiotoxicity Management with Mesenchymal Stem Cells and Their Derivatives: A Focus on Radiation-Induced Cystitis
Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.
research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing: A Review of Experimental Models and Future Perspectives
Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
research Opening New Horizons in Regenerative Dermatology Using Platelet-Based Autologous Therapies
Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.
research Camellia Seed Cake Extract Supports Hair Growth by Abrogating the Effect of Dihydrotestosterone in Cultured Human Dermal Papilla Cells
Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
research Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway
Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
research Congenital Cutaneous Lymphadenoma
An 8-year-old girl had a rare, benign skin tumor on her forehead.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Potential Natural Products Regulation of Molecular Signaling Pathway in Dermal Papilla Stem Cells
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia
Micrografts improve hair density and thickness without side effects.
research Hair Cycle Control by Leptin as a New Anagen Inducer
Leptin, a hormone, is important for starting hair growth.
research PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration
PI3K/Akt pathway is crucial for hair growth and regeneration.
research All-Trans-Retinoic Acid Inhibits Mink Hair Follicle Growth by Inhibiting Proliferation and Inducing Apoptosis of Dermal Papilla Cells Through TGF-β2/Smad2/3 Pathway
All-trans-retinoic acid stops mink hair growth by affecting cell growth and causing cell death.
research Distinct Expression Profile of Stem Cell Markers, LGR5 and LGR6, in Basaloid Skin Tumors
LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.