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    Research 181–210 of 773

    1. The Rotterdam Study: objectives and design update European Journal of Epidemiology · 2007 · 1415 citations
    2. First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors Journal of clinical oncology · 2011 · 505 citations
    3. Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics Journal of Clinical Medicine · 2023 · 380 citations
    4. The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic Frontiers in Public Health · 2022 · 238 citations
    5. Intradermal adipocytes mediate fibroblast recruitment during skin wound healing Development · 2013 · 238 citations
    6. Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog Journal of Clinical Investigation · 1999 · 231 citations
    7. Prostaglandin D <sub>2</sub> Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012 · 205 citations
    8. Lactate dehydrogenase activity drives hair follicle stem cell activation Nature cell biology · 2017 · 202 citations
    9. Wnt signaling induces epithelial differentiation during cutaneous wound healing BMC Cell Biology · 2006 · 159 citations
    10. LPA-producing enzyme PA-PLA<sub>1</sub>α regulates hair follicle development by modulating EGFR signalling The EMBO Journal · 2011 · 151 citations
    11. Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration Stem Cell Research & Therapy · 2022 · 148 citations
    12. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis 2008 · 148 citations
    13. Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway Stem Cell Research & Therapy · 2020 · 139 citations
    14. Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism PLoS Medicine · 2006 · 135 citations
    15. Human acellular amniotic membrane incorporating exosomes from adipose-derived mesenchymal stem cells promotes diabetic wound healing Stem Cell Research & Therapy · 2021 · 132 citations
    16. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors Proceedings of the National Academy of Sciences of the United States of America · 2014 · 130 citations
    17. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF Nature Communications · 2017 · 117 citations
    18. Autosomal Ichthyosis with Hypotrichosis Syndrome Displays Low Matriptase Proteolytic Activity and Is Phenocopied in ST14 Hypomorphic Mice Journal of Biological Chemistry · 2007 · 101 citations
    19. Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2 Cell Research · 2021 · 100 citations
    20. Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice Journal of Investigative Dermatology · 2011 · 100 citations
    21. A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity The Journal of Cell Biology · 2015 · 98 citations
    22. Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation Stem Cell Research & Therapy · 2020 · 90 citations
    23. Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin Physiological Genomics · 2004 · 90 citations
    24. Extracellular vesicles as human therapeutics: A scoping review of the literature Journal of Extracellular Vesicles · 2024 · 88 citations
    25. Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress PLOS genetics · 2014 · 88 citations
    26. Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells – Evidence of its Presence in Melanocytes Journal of Investigative Dermatology · 1998 · 83 citations
    27. p63 Regulates Human Keratinocyte Proliferation via MYC-regulated Gene Network and Differentiation Commitment through Cell Adhesion-related Gene Network Journal of Biological Chemistry · 2011 · 82 citations
    28. Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells Molecular Biology of the Cell · 2002 · 80 citations
    29. Dynamic Plasticity of Axons within a Cutaneous Milieu Journal of Neuroscience · 2010 · 79 citations
    30. Chronic Restraint Stress Inhibits Hair Growth via Substance P Mediated by Reactive Oxygen Species in Mice PLoS ONE · 2013 · 76 citations