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Understanding and managing side effects of hedgehog pathway inhibitors can improve treatment for advanced basal cell carcinoma.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Adverse events from vismodegib can be managed effectively to ensure optimal treatment.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Most people with basal cell carcinoma on their head or neck were 60-70 years old, and it often came back even after being fully removed, especially in certain areas and types.

Mice with damaged skin or hair follicles are more susceptible to anthrax infection.

New treatments for a type of skin cancer show promise but have side effects and may work better with other therapies.

Activating Notch signaling can kill basal cell carcinoma cells.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Photodynamic therapy was effective in treating multiple scalp basal cell carcinomas with minimal side effects and good cosmetic results.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.

Heterotypic cell contacts likely help hair matrix cells differentiate during mouse hair follicle development.

The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.

CK 15, follistatin, and Bmi-1 can help differentiate basal cell carcinoma from squamous cell carcinoma.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

CD99 is highly present in certain skin cells and could help treat skin conditions.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.

Bacillus subtilis strain WM13-24 helps plant root growth through volatile compounds.

BerEP4 and CD34 staining can help tell apart tricholemmoma from basal cell carcinoma.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.

Basal cell carcinomas may differentiate similarly to hair follicles and could be influenced by hair cycle-related treatments.

A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.

Dr. Connelly agrees that linear basal cell carcinomas might be more aggressive but highlights the study's lack of clear criteria to identify them.

The review found that basal cell carcinomas on the scalp are not more aggressive than those in other locations.