44 citations
,
March 2016 in “Frontiers in cellular neuroscience” In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.
44 citations
,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
43 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews innovations in hair cosmetics, focusing on esthetic procedures and products in the Indian market, and reports no new experimental findings.
42 citations
,
January 2024 in “Frontiers in Endocrinology” This review discusses polycystic ovary syndrome treatments, focusing on the potential benefits and safety of herbs and phytochemicals, and reports no new clinical results.
39 citations
,
June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” This review examines around 68 plant sources from six major plant families, assessing their scientific rationale and use by the cosmeceutical industry for applications like anti-ageing and sun protection.
39 citations
,
September 2013 in “Journal of Cosmetic Dermatology” This review summarizes causes and treatments of androgenetic alopecia with a focus on herbs as potential alternatives, but reports no new results and suggests more research is needed to validate these options.
36 citations
,
August 2021 in “Nature Cell Biology” This review discusses the potential of organoids in modeling COVID-19 disease and developing therapies, without reporting new results, and highlights opportunities and challenges in their application for research.
34 citations
,
April 2009 in “Expert Opinion on Pharmacotherapy” This review discusses evidence-based treatments for common hair loss forms, noting robust support for androgenetic alopecia therapies but limited long-term data and fewer high-quality studies for alopecia areata and cicatricial alopecias.
33 citations
,
January 2018 in “The International Journal of Developmental Biology” This review discusses the dual role of cellular senescence in ageing and tissue repair and suggests potential therapeutic applications, with no new experimental results reported.
33 citations
,
September 2016 in “Lasers in Surgery and Medicine” In this review, the authors report that fractional resurfacing can be a safe and effective technique for treating scars and promoting photorejuvenation in Asian skin, though it requires cautious use to minimize risks like post-inflammatory hyperpigmentation and rebound melasma.
32 citations
,
January 2021 in “Molecules” This review compiles studies on the antidiabetic potential of plants from the Middle East, particularly from the Asteraceae and Lamiaceae families, but reports no clinical results.
32 citations
,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” This review discusses the emerging roles of transit-amplifying cells in tissue regeneration and cancer formation, highlighting their significance beyond a mere transitional state in hair follicles and the hematopoietic system.
32 citations
,
November 2016 in “Journal of Dental Research” This review explores the role of Panx3 in skeletal formation and discusses its potential in developing new therapies for conditions like osteoarthritis, without presenting new clinical findings.
31 citations
,
May 2021 in “Journal of endocrinological investigation” This study in Italy found that APS-1, a rare disorder, is associated with various AIRE gene mutations and most individuals have autoantibodies such as IFNωAbs, which are markers of the condition.
29 citations
,
September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
28 citations
,
August 2015 in “Journal of Drug Targeting” This study found that a novel proniosomal gel formulation of CoQ10 improved antioxidant levels and provided better skin protection against UV radiation compared to a conventional CoQ10 gel in animal models.
28 citations
,
February 2020 in “Clinical Ophthalmology” This article discusses intraoperative floppy iris syndrome during cataract surgery and highlights the importance of awareness and preoperative documentation of its risk factors, emphasizing a multidisciplinary approach to management.
27 citations
,
November 2020 in “International Journal of Dermatology” This review examined dermatologic symptoms associated with COVID-19 in 2,560 patients, with chilblains/pernio-like lesions being the most common, suggesting these symptoms may aid in early identification of cases.
27 citations
,
January 2018 in “Curēus” This review discusses the complications of subcutaneous contraception and emphasizes the importance of adequately counseling patients on potential side effects to aid informed decision-making; however, it reports no new clinical results.
26 citations
,
October 2023 in “Neuroscience Bulletin” In this review, the authors discuss how understanding and co-regulating multiple signaling pathways could lead to effective regeneration of functional hair cells, highlighting current achievements and future approaches such as small molecule drugs and gene therapy for treating sensorineural hearing loss.
26 citations
,
August 2018 in “American Journal of Clinical Dermatology” This review discusses the clinical characteristics of alopecia in cancer patients, highlighting its potential role as an associated finding or diagnostic clue, but reports no new clinical results.
25 citations
,
March 2018 in “Clinics in Dermatology” This review discusses traditional therapies used in the Indian subcontinent, covering practices like Ayurveda and homeopathy, and reports no new clinical results; the authors emphasize the need for rigorous studies.
25 citations
,
July 2017 in “Archives of Dermatological Research” This review summarizes preclinical and clinical information on herbal products for hair loss treatment, highlighting their mechanisms, follicular penetration, and potential side effects, suggesting they may offer alternatives to synthetic drugs with fewer side effects.
25 citations
,
February 2019 in “Genomics” This study reports that milk goats exhibit significantly more differentially expressed genes related to hair follicle cycling across different months compared to cashmere goats, especially in December.
25 citations
,
January 2019 in “Annals of Dermatology” This study observed that the NOTCH signaling pathway may contribute to the development of fibrosis in systemic sclerosis by affecting epithelial cell changes, and inhibiting this pathway could prevent fibrosis in experimental models.
25 citations
,
November 2018 in “Cell reports” This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.
25 citations
,
August 2007 in “Molecular Therapy” This study found that using ectopic expression of CD24 is a promising approach for selecting genetically modified human epidermal stem cells for safe cutaneous gene therapy in cancer-prone conditions.
25 citations
,
December 2001 in “Expert Opinion on Pharmacotherapy” This review discusses the therapeutic potential of potassium channel openers for various conditions, but notes that their clinical role is not yet fully established.
24 citations
,
October 2024 in “Process Biochemistry” In this study, Gaussian process regression models combined with Grey Wolf optimization were used to predict and optimize phenolic and flavonoid content extraction from Carthamus caeruleus L. rhizomes, showing high accuracy and helping improve understanding and extraction processes through a new interactive tool.
23 citations
,
January 2009 in “Veterinary Dermatology” This study found that recombinant hepatitis B vaccine may increase the risk of alopecia areata onset in older predisposed mice but larger trials suggest this effect might lie within normal variation.