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The document suggests that severe hair loss in SLE patients may be an early sign of scalp DLE, treatable with immunosuppressive therapy.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

The study created a new method to test drugs that affect hormone processing in skin.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Topical vitamin D is effective in treating vitiligo with few side effects.

The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.

Lichen planopilaris in men often involves scalp redness and itching, with some also having hair loss, mucosal lichen planus, or thyroid disease, and treatment improved symptoms in nearly half of the cases.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.

Some types of extracellular matrix can change how human skin cells grow but don't affect their basic functions.

DDS treatment for LABD can cause severe side effects like anemia and hair loss, requiring careful monitoring.

Transplanting a mix of specific skin cells can significantly improve the repair of damaged hair follicles.

Scalp biopsy helps tell apart permanent and temporary hair loss types and guides treatment.

Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.

Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.

TLR2 is important for hair growth and can be targeted to treat hair loss.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

CD4+ skin cells may be precursors to basal cell carcinoma.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

High doses of Lepidium sativum seed extract are toxic and should be used with caution.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

New scaffold materials help heal severe skin wounds and improve skin regeneration.

The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.

Triple horizontal scalp biopsies are 98% accurate in diagnosing hair loss, better than single biopsies.