research Early Inductive Events in Ectodermal Appendage Morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
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research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Beyond Goosebumps: Does the Arrector Pili Muscle Have a Role in Hair Loss?
The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
research Hyperadrenocorticism (Cushing’s Disease or Syndrome) in Dogs: Treatment Approaches and Prognosis
Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
research Epithelial Stem Cells: Turning Over New Leaves
Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
research The Hair Cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research The Hair Cycle
The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Recently Identified Forms of Epidermolysis Bullosa
Three new types of a skin blistering disease were found, caused by specific gene mutations.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research Use of Extracellular Matrix Hydrogel from Human Placenta to Restore Hair-Inductive Potential of Dermal Papilla Cells
Human placenta hydrogel helps restore cells needed for hair growth.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Stem Cells Behind the Barrier: Mechanisms Regulating Epidermal Stem and Progenitor Cell Differentiation
Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
research Commentary: Unroofing for Hidradenitis Suppurativa, Why and How
Unroofing is an effective, less invasive, and cost-effective surgery for hidradenitis suppurativa with low recurrence and improved patient quality of life.
research Dermatopathology and Molecular Genetics
Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.
research Steroid-Sparing Effect of Mycophenolate Mofetil in the Treatment of a Subepidermal Blistering Autoimmune Disease in a Dog: Clinical Communication
Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.
research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Use of Urinary Bladder Matrix, a Bioactive, Acellular Scaffold, in Transplant Donor Scars and Androgenetic Alopecia: Initial Clinical Experience
UBM helps hair regrowth in men and women with hair loss.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Endoplasmic Reticulum Stress Upregulates NKG2D Ligands in the Hair Follicle
Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
research Scalp Sebaceous Physiology
The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.
research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research Genetics of Blond Hair
Blond hair in Solomon Islanders is due to a unique genetic variant, not European ancestry.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin
Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
research Skin Wound Healing in Humans and Mice: Challenges in Translational Research
The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
research Critical Stages of Hair Development and Pigmentation in the Mouse
Hair growth and pigmentation in mice involve specific stages crucial for research.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.