October 2024 in “Biology” Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
April 2024 in “Biomolecules” Exosomal miRNAs from stem cells can help improve skin health and delay aging.
March 2024 in “Tissue and cell/Tissue & cell” Telomerase-positive cells are mainly in the bulb matrix and outer root sheath of hair follicles.
May 2023 in “Stem cell research & therapy” New method efficiently isolates hair growth cells from newborn mouse skin.
July 2022 in “Journal of Investigative Dermatology” The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.
375 citations,
February 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
314 citations,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
196 citations,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
103 citations,
January 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
94 citations,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
92 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
64 citations,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
57 citations,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
51 citations,
July 2013 in “Bioorganic & Medicinal Chemistry Letters” Compounds from Polygonum multiflorum root, especially a new one, can boost hair growth more effectively than common treatments.
45 citations,
May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
43 citations,
January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.
40 citations,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” S100A3 protein is crucial for hair shaft formation in mice.
33 citations,
May 2018 in “Stem Cell Reports” Krt15+ cells in the mouse intestine resist radiation and can start tumors.
33 citations,
December 2015 in “International Journal of Molecular Sciences” Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
32 citations,
February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
30 citations,
November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
25 citations,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
17 citations,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
8 citations,
February 2021 in “Journal of Clinical Medicine” Hair follicle stem cells are promising for blood vessel formation and tissue repair.
8 citations,
February 2021 in “Biomolecules & therapeutics” Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
7 citations,
March 2022 in “Molecules” 5-Bromo-3,4-dihydroxybenzaldehyde could potentially help hair growth by activating certain cell pathways and inhibiting others.
7 citations,
February 2022 in “Stem cell reviews and reports” Skin cells show flexibility in healing wounds and forming tumors, with potential for treating hair disorders and chronic ulcers.
5 citations,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.