12 citations
,
June 2013 in “International Journal of Dermatology” This study found that different types of seborrheic keratosis demonstrate diverse differentiation patterns, highlighting its undifferentiated and hyperproliferative state with varying keratinization directions.
3 citations
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June 2023 in “Modern Pathology” This study found that GLI1 RNA CISH was highly sensitive and specific for distinguishing basal cell carcinoma from nonfollicular epithelial neoplasms but not from most benign follicular tumors.
January 2008 in “Deep Blue (University of Michigan)” This study found that Hedgehog-driven skin tumorigenesis is dependent on the Wnt/beta-catenin signaling pathway and suggests that targeting Wnt ligands could be a potential therapeutic strategy.
1 citations
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January 2012 in “Journal of Toxicologic Pathology” This case report describes a hybrid cyst in a Sprague-Dawley rat, showing both infundibular and matrical differentiation similar to different parts of normal hair follicles.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.
September 2020 in “Oral surgery, oral medicine, oral pathology and oral radiology” This case report describes a pilomatricoma in a 21-year-old woman, highlighting the diagnostic process and illustrating the potential for intraoral surgical access to minimize scarring.
January 2025 in “Indian Journal of Dermatopathology and Diagnostic Dermatology” In this histopathology study of nevus sebaceus, researchers observed distinct epidermal, sebaceous, follicular, and apocrine changes, including sebaceous hyperplasia and basaloid adnexal proliferation, which help differentiate it from similar conditions like basal cell carcinoma and trichoblastoma.
4 citations
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August 2017 in “Journal of cutaneous pathology” This case report documents only the second known instance of congenital lymphadenoma, expanding the diagnostic possibilities for cutaneous lymphoepithelial tumors in children.
January 2003 in “Linchuang pifuke zazhi” This case report describes a trichoblastoma in a 58-year-old man's leg, which was successfully excised without recurrence observed after 9 months.
3 citations
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December 2003 in “Archives of Pathology & Laboratory Medicine” This article reviews the distinctive features of cutaneous lymphadenoma, a variant of trichoblastoma, and its differential diagnosis, but it presents no new empirical results.
March 2022 in “Veterinary dermatology” This case report provides the first evidence of clinical and histopathological findings of cutaneous diffuse basaloid follicular hamartomas in a young domestic short hair cat.
June 2025 in “Indian Journal of Dermatology” This article reports a case of late onset linear and unilateral basaloid follicular hamartoma in an elderly male, highlighting the clinical presentation, histopathological findings, and planned treatment approach.
30 citations
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December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.
21 citations
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April 2000 in “Journal of Cutaneous Pathology” This case report describes a 22-year-old woman with a nevoid plaque termed localized follicular hamartoma, characterized by skin-colored papules and specific cellular and structural features.
2 citations
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August 2025 in “Reports — Medical Cases Images and Videos” In this case report, a rare melanotrichoblastoma tumor was identified in a 51-year-old female following the histological and immunohistochemical analysis of a lesion on the pubo-inguinal area, presenting with strong epithelial marker positivity and a low proliferative index.
21 citations
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January 2018 in “Anticancer Research” This study suggests that NBCCS and BFHS may be the same genetic condition, which could help improve identification and management of misdiagnosed cases with specific surveillance strategies.
9 citations
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January 2017 in “Virchows Archiv” This study documented distinct expression patterns of stem cell markers LGR5 and LGR6 in various human skin tumors, highlighting differences in their potential roles and contributions to tumor development.
1 citations
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December 2018 in “Journal of cutaneous pathology” This study found that 11% of cutaneous focal mucinosis lesions demonstrated follicular induction, which can mimic basal cell carcinoma histologically and complicate diagnosis.
178 citations
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April 2011 in “Journal of Clinical Investigation” This study found that the phenotype of Hedgehog/Gli-driven skin tumors in mice depends on the cell of origin, tissue context, and level of oncogenic signaling.
August 2021 in “Annals of pathology and laboratory medicine” This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.
June 2025 in “Histopathology” This study found that in superficial angiomyxomas, S100A4-positive mesenchymal niches may induce non-neoplastic adnexal epithelial growth, and highlighted evidence of mesenchymal-to-epithelial transition in eccrine duct branching, especially in Carney's complex cases.
2 citations
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February 2009 in “Clinical and Experimental Dermatology” In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.
34 citations
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February 2012 in “Journal of Cutaneous Pathology” This research retrospectively evaluated 92 skin specimens to propose histopathological criteria for diagnosing alopecia areata incognito, distinguishing it from telogen effluvium and androgenetic alopecia.
8 citations
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July 2015 in “European journal of histochemistry” This study found that Sox9 was variably expressed in most canine skin neoplasms, particularly in those originating from the hair follicle's bulge region, suggesting its potential as a stem cell marker.
146 citations
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February 2012 in “Journal of Clinical Investigation” This review discusses the role of Hedgehog signaling in basal cell carcinoma development and highlights genetic mouse models and potential targeted therapies, but reports no new clinical results.
3 citations
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April 2016 in “International Journal of Dermatology” This article presents a clinicopathologic challenge involving early leonine facies with alopecia in a young man and reports no new clinical results.
7 citations
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April 2012 in “Biomolecular concepts” This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.
57 citations
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February 2006 in “Journal of Investigative Dermatology” Cylindromas likely originate from hair follicle stem cells, not sweat glands.
May 2020 in “International journal of dermatology and venereology” This study introduces the term "hair matrix cyst" for a cyst with both pilomatricoma and epidermal cyst characteristics, highlighting its potential for misdiagnosis among similar skin conditions.
December 2021 in “Pathologica” This case report describes a rare instance of trichogerminoma with unusually numerous mitotic figures and a higher Ki67 proliferative rate, distinguishing it from previously documented cases.