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Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Chromosomal differences affect how muscle cells respond to testosterone.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

A woman was allergic to quinine in her anti-hair loss lotion.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Trilostane may help delay epilepsy development by increasing certain brain chemicals.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Anabolic steroid users may face higher risk of severe COVID-19.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.