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The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.

The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Embryonic and adult stem cells are valuable for improving skin grafts and cell therapy.

Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.

Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.

Removing integrin α3β1 from hair stem cells lowers skin tumor growth by affecting CCN2 protein levels.

Hair follicle stem cells have significant potential for treating various disorders.

Activating Nrf2 helps wounds heal faster by increasing hair follicle stem cells.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Apoptosis is essential for human skin development and forming a functional epidermis.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.