research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
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research Pharmacological Activation of Estrogen Receptors-α and -β Differentially Modulates Keratinocyte Differentiation with Functional Impact on Wound Healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
research P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss
Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Histopathological and Immunohistochemical Study of Trichoblastoma in the Rabbit
Trichoblastomas in rabbits are linked to uncontrolled embryonic hair growth and have distinct histological features.
research Development and Homeostasis of the Sebaceous Gland
The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.
research Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation
Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
research Intravital Imaging of Hair Follicle Regeneration in the Mouse
Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.
research Wnt Signaling: The Good and the Bad
Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research Hair Matters in Melanoma Biology
The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.
research Analysis of Thymosin β4 and Vascular Endothelial Growth Factor Expression in Normal Human Tissues Using Tissue Microarray
Thymosin β4 and VEGF are important for blood vessel formation in many organs.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Module-Based Complexity Formation: Periodic Patterning in Feathers and Hairs
The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
research Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research Ultrastructural and Immunohistochemical Characteristics of Telocytes in Human Scalp Tissue
Telocytes in the scalp may help with skin regeneration and maintenance.
research Cutaneous Transcriptome Analysis in NIH Hairless Mice
Key genes linked to hair growth and cancer were identified in hairless mice.
research Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid
Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
research Stretching the Limits: From Homeostasis to Stem Cell Plasticity in Wound Healing and Cancer
Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research The Spectrum of Scarring in Craniofacial Wound Repair
Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research The Thrill of Scientific Discovery and Leadership with My Group
The author felt excited and honored to receive the 2016 Early Career Life Scientist Award.
research The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding
Vitamin D receptor is crucial for skin wound healing.
research Localization of Members of the Notch System and the Differentiation of Vibrissa Hair Follicles: Receptors, Ligands, and Fringe Modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
research Plucked Human Hair Shafts and Biomolecular Medical Research
Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
research Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device
A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta
Targeting TGFβ can improve skin immunity in older people.