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Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Malnutrition severely harms growth and development in young baboons.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Spermidine helps protect against aging by preserving telomere length.

Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.

The document discusses various challenging skin conditions and their treatments.

Patients with acne vulgaris have lower serum irisin levels.

Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Clomipramine may significantly reduce hair-pulling in Trichotillomania, but more research is needed on treatments and early onset cases.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Finasteride affects prostate weights and pituitary activity differently with age.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.

Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.

Caffeine improves hair growth, thickness, and reduces shedding.

Diet affects baldness; eat balanced, less animal fat, more fruits, vegetables, and cereals.

Innovative methods are reducing animal testing and improving biomedical research.

Thyroid hormone may be useful for treating various skin conditions and needs more research.

Beta-blockers and anti-anginal medications have various side effects and interactions that require careful monitoring and individualized treatment.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

SCD1 is crucial for skin health and overall energy balance.

Light therapy can stimulate hair growth and is more effective when started early, but more research is needed on its long-term effects and optimal use.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.