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The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

Wounded skin cells can revert to stem cells and help heal.

Skin organoids help improve wound healing and tissue repair.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Hairless protein can block vitamin D activation in skin cells.

Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Early intervention and tailored management can reduce skin side effects from cancer treatments.

Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Scientists found a new type of skin cell that could help with skin repair and these cells work better with a certain protein.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.