120 citations,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
5 citations,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
1 citations,
September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
25 citations,
April 1949 in “The journal of experimental zoology” Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
8 citations,
July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
74 citations,
November 2000 in “Archives of Dermatology” Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
24 citations,
November 2016 in “Cell death and disease” Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.
22 citations,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
62 citations,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
60 citations,
November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
43 citations,
January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
39 citations,
July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
23 citations,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
9 citations,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
150 citations,
December 2012 in “EMBO Reports” Stem cell self-renewal is complex and needs more research for full understanding.
11 citations,
September 2016 in “Journal of virological methods” Rabies virus was found in specific skin cells of rabid dogs' muzzles, suggesting these cells could help diagnose rabies.
168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
179 citations,
July 2016 in “Nature Reviews Molecular Cell Biology” Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
54 citations,
January 2009 in “British Journal of Dermatology” Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
18 citations,
September 1990 in “Veterinary Dermatology” Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.
14 citations,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.