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    Research 631–660 of 1000+

    1. The Rotterdam Study: 2018 update on objectives, design and main results European Journal of Epidemiology · 2017 · 359 citations
    2. Integrin signalling regulates YAP/TAZ to control skin homeostasis Development · 2016 · 266 citations
    3. Serotoninergic and melatoninergic systems are fully expressed in human skin ˜The œFASEB journal · 2002 · 249 citations
    4. The Rotterdam Study: 2012 objectives and design update European Journal of Epidemiology · 2011 · 247 citations
    5. Tracing the cellular origin of cancer Nature Cell Biology · 2013 · 232 citations
    6. Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter Journal of Investigative Dermatology · 2000 · 215 citations
    7. Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair EMBO journal · 1999 · 204 citations
    8. Abnormal differentiation of epidermis in transgenic mice constitutively expressing cyclooxygenase-2 in skin Proceedings of the National Academy of Sciences · 2001 · 201 citations
    9. Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes Journal of Investigative Dermatology · 1999 · 198 citations
    10. Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation. The Journal of Cell Biology · 1989 · 198 citations
    11. Hedgehog signalling in skin development and cancer Experimental Dermatology · 2006 · 190 citations
    12. Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus PLoS Genetics · 2006 · 184 citations
    13. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006 · 176 citations
    14. GLI2 Is Expressed in Normal Human Epidermis and BCC and Induces GLI1 Expression by Binding to its Promoter Journal of Investigative Dermatology · 2004 · 171 citations
    15. p63 expression in normal skin and usual cutaneous carcinomas Journal of Cutaneous Pathology · 2002 · 157 citations
    16. A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin. Genes & Development · 1989 · 156 citations
    17. Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell? Cell Stem Cell · 2007 · 153 citations
    18. Cutaneous adverse effects of targeted therapies Journal of the American Academy of Dermatology · 2015 · 149 citations
    19. Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors Clinical Cancer Research · 2013 · 136 citations
    20. Keratins of the human hair follicle: “Hyperproliferative” keratins consistently expressed in outer root sheath cells in vivo and in vitro Differentiation · 1987 · 135 citations
    21. Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals Proceedings of the National Academy of Sciences · 2005 · 130 citations
    22. The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis PloS one · 2008 · 127 citations
    23. Cytokeratins as Markers of Follicular Differentiation American Journal of Dermatopathology · 2001 · 121 citations
    24. Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation 2008 · 120 citations
    25. Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells Stem cells · 2017 · 105 citations
    26. Targeting of Smoothened for therapeutic gain Trends in Pharmacological Sciences · 2014 · 105 citations
    27. Human Eccrine Sweat Gland Cells Can Reconstitute a Stratified Epidermis Journal of Investigative Dermatology · 2010 · 103 citations
    28. An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis Development · 2004 · 99 citations
    29. Contact cooling of the skin Physics in Medicine and Biology · 1999 · 92 citations
    30. Epidemiology of skin cancer in the mature patient Clinics in Dermatology · 2017 · 86 citations