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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Human skin can make serotonin and melatonin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Targeted cancer therapies often cause skin side effects, needing dermatologist care.

Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

High-frequency ultrasonography is a useful but underused tool in dermatology for assessing skin cancers, monitoring diseases, and evaluating treatments.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Acne is the most common skin problem in Brazil, with a need for improved dermatological care and health education, especially for the public sector and black-skinned individuals.

The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.

GLI2 increases follistatin production in human skin cells.

Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.

Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

The extracellular matrix affects where tumors can start in the body.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

The first in-prison dermatology clinic in the U.S. faced challenges and found certain skin conditions common among inmates, with rare cases of serious skin cancer.

Germany recognizes skin cancer from UV exposure as an occupational disease, emphasizing prevention and care for affected workers.

Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.

Some skin tumors may start from hair follicle stem cells.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

Most cutaneous adnexal tumors examined were benign and resembled common skin tumors.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Technique effectively reconstructs large scalp defects with minimal hair loss and visible scarring.

The technique of using a skin and hair graft from behind the ear successfully reconstructed a large eyebrow defect with good cosmetic results.

Hedgehog pathway inhibitors used for skin cancer can cause significant hair loss, which may improve after stopping the medication.

Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.