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Tumor cell adhesion is linked to higher risk of SLN metastasis and melanoma recurrence, and a model including these factors predicts these outcomes better than one with just clinical data.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

The number of new cases of cutaneous B-cell lymphoma has leveled off since the early 2000s, and survival rates have improved since 1973.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

Different types of stem cells and their environments are key to skin repair and maintenance.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Improving the environment and cell interactions is key for creating human hair in the lab.

The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.