research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
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research Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration
New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research Matricellular Proteins in the Homeostasis, Regeneration, and Aging of Skin
Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
research Retinoic Acid-Induced Epidermal Transdifferentiation in Skin
Retinoic acid helps change skin cells and is important for skin development and hair growth.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Orchestrated Role of MicroRNAs in Skin Development and Regeneration
MicroRNAs are crucial for skin development, regeneration, and disease treatment.
research The Expanding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
research Folliculin Interacts With P0071 (Plakophilin-4) and Deficiency Is Associated With Disordered RhoA Signalling, Epithelial Polarization, and Cytokinesis
Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.
research MicroRNAs in Skin Tissue Engineering
MicroRNAs could improve skin tissue engineering by regulating cells and changing the skin's bioactive environment.
research Regulation of the Wound Healing Response During Aging
Aging slows wound healing due to weaker cells and immune response.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Cutaneous Retinoic Acid Levels Determine Hair Follicle Development And Downgrowth
The right amount of retinoic acid is essential for normal hair growth and development.
research Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-Communicable Chronic Disease
Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
research Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model
Minoxidil-loaded hyaluronic acid microneedles can effectively increase hair growth and could be a promising treatment for hair loss.
research Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit
Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
research Transplanted Hair Follicle Mesenchymal Stem Cells Alleviated Small Intestinal Ischemia–Reperfusion Injury via Intrinsic and Paracrine Mechanisms in a Rat Model
Transplanted hair follicle stem cells can heal damaged rat intestines.
research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome: A Review
Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
research A Finasteride Patch for the Treatment of Androgenetic Alopecia: Study on Permeability Strategy Using Synthetic O-Acylmenthols and Ion-Pair
The finasteride patch effectively treats hair loss by enhancing skin absorption.
research Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration
Regenerative cosmetics can improve skin and hair by reducing wrinkles, healing wounds, and promoting hair growth.
research Comparative Analysis of mRNA and miRNA Expression Between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak
Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.
research Ectopic Odorant Receptors Responding to Flavor Compounds in Skin Health and Disease: Current Insights and Future Perspectives
Skin odorant receptors respond to flavors and could be targeted to improve skin health and treat diseases.
research Erosive Pustular Dermatosis: A Manifestation of Immunosenescence - A Report of 8 Cases
Erosive pustular dermatosis in elderly people may be linked to aging immune systems and skin damage.
research Gene Expression Profile of Human Follicle Dermal Papilla Cells in Response to Camellia Japonica Phytoplacenta Extract
Camellia japonica extract may improve scalp health and promote hair growth.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Effect of an Oral Probiotic Formula on Scalp and Facial Skin Condition, Glucose, and Lipid Metabolism
Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.
research Cutaneous Responses to Systemic Iron: A Potential Role for Epidermal Turnover in Mammalian Iron Excretion
Skin may help in getting rid of excess iron through the process of skin cell renewal.
research Plain Language Summaries of Dermatological Studies
Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.