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The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Spironolactone most effective for hirsutism, but has side effects.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Hair shedding is an active process that could be targeted to treat hair loss.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.

RANK-RANKL signaling is essential for hair growth and skin health.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Researchers found 15 new genetic links to skin traits in Japanese women.

Products should be called 'sperm-safe' only after thorough, well-designed tests.