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Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

The 2017 issue emphasized progress in laser and energy-based skin treatments, but noted the need for more research on certain procedures and technologies.

Tailoring facial plastic surgery to different ethnic groups ensures natural and satisfactory results.

FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Potassium levels affect blood sugar and insulin during dialysis, and malnutrition changes children's hair roots.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Black bean, wheat, and rice bran extracts can boost hair growth and improve hair quality.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

A woman with breast cancer developed a rare condition causing excessive fine hair growth on her face and body.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Early-stage Alopecia Areata was effectively treated in less than six months.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

Mice with alopecia areata had wider lymphatic vessels in their skin.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Finasteride, often used for hair loss, can potentially cause cataracts.

A baby boy with 13q deletion syndrome had eye cancer, a woman's vision improved after stopping a breast cancer drug, a man developed cataracts from using Propecia, and a rare skin disorder called Lipoid Proteinosis was discussed. Also, a tool called OCT is useful for diagnosing macular diseases.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.

Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.

Persistent radiation-induced hair loss is dose-dependent, and treatments like topical minoxidil can be effective.