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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Hair loss can cause low self-esteem, anxiety, and depression in men.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Finasteride effectively treats frontal hair loss with few side effects.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Finasteride helps hair growth but may cause sexual side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.