264 citations
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October 1958 in “Archives of Dermatology” This report describes a 1949 case of a young girl with a rare congenital ectodermal defect causing unique hair fragility, which had not been previously documented in the literature.
December 2025 in “Clinical Case Reports” In this study, researchers reported that dermoscopic examination of eyebrow hairs can help in the early diagnosis of Netherton syndrome in children by detecting trichorrhexis invaginata, facilitating prompt counseling and care while awaiting genetic test results.
3 citations
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May 2017 in “BMJ Case Reports” This case report details a 15-year-old boy who developed iatrogenic Cushing’s disease with severe complications after prolonged treatment by an untrained practitioner for persistent erythroderma.
April 2017 in “IOSR journal of dental and medical sciences” This abstract discusses Netherton Syndrome, a genetic disorder with a characteristic triad of symptoms caused by SPINK5 gene mutation, and reports no new clinical findings or treatment advances.
August 2011 in “SpringerReference” 72 citations
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July 1984 in “Journal of Investigative Dermatology” July 1990 in “British Journal of Dermatology” 58 citations
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November 1969 in “British Journal of Dermatology” This report describes two patients with ichthyosis linearis circumflexa exhibiting symptoms resembling Netherton's disease, noting multiple hair shaft defects and discussing a possible connection to aminoaciduria.
41 citations
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December 2008 in “Pediatric Dermatology” This case report indicates that trichoscopy may significantly improve the diagnosis of Netherton syndrome by noninvasively identifying typical hair abnormalities without the need to pull hair.
June 2026 in “Case Reports in Dermatology” This case study reported that in a 67-year-old woman with Netherton syndrome, treatment with dupilumab improved skin inflammation and pruritus and was associated with significant improvements in hair growth and structure, including the resolution of "bamboo" hair.
January 2019 in “Global Dermatology” This review discusses the genetic disorder, monilethrix, characterized by fragile, brittle hair and its inheritance patterns, and reports no new clinical results.
July 2018 in “Elsevier eBooks” This chapter details the causes and diagnostic process of pediatric alopecia, including trichoscopic findings, but reports no new clinical results.
24 citations
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January 1969 in “Archives of Dermatological Research” Hair malformations may occur due to timing issues in hair development.
9 citations
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April 1985 in “Archives of Dermatology” This case report describes a 7-year-old boy with Netherton's syndrome, highlighting the identification of the tricorrhexis invaginata hair defect using a photographically illustrated scalp biopsy, which had not been visually documented before.
In this case report, a 67-year-old woman with Netherton syndrome experienced significant improvement in skin inflammation, pruritus, and hair growth after treatment with dupilumab, suggesting potential benefits for addressing both cutaneous and hair manifestations of the condition.
This case study documented that a 67-year-old woman with Netherton syndrome experienced significant improvements in skin inflammation, pruritus, and hair growth after treatment with dupilumab, addressing symptoms of the syndrome and showing promising results for resolving "bamboo" hair.
November 2021 in “CRC Press eBooks” This article reviews various congenital and acquired hair shaft disorders, examining their characteristics and potential links to wider health conditions, but does not present any new clinical results.
January 2006 in “Dianzi xianwei xuebao” This study observed that ultrastructural changes like lamellar bodies and electron-dense granules in the stratum corneum may aid in the early diagnosis of Netherton syndrome.
November 2024 in “Journal of Natural Remedies” This article reviews the use of herbal ingredients in hair care products, highlighting their potential benefits for scalp health, hair growth, and condition, while also discussing challenges such as individual sensitivities and the importance of transparent labeling.
In this study, women with acute telogen effluvium taking the Hair’InsideTM supplement for 84 days showed significant improvements in hair regrowth, shedding, brightness, and volume compared to placebo, with no reported adverse effects.
October 2025 in “Indian Journal of Paediatric Dermatology” In this case report, a 6-year-old boy with Netherton syndrome was diagnosed using trichoscopy, which revealed characteristic hair shaft abnormalities such as bamboo, golf tee, and matchstick hairs.
30 citations
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February 2015 in “Anais Brasileiros de Dermatologia” This case report describes a 4-year-old boy with Netherton syndrome, where trichoscopy importantly aided diagnosis and is recommended for all children with erythroderma.
4 citations
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April 1978 in “PubMed” This case study describes a six-month-old boy diagnosed with Netherton syndrome, featuring ichthyosiform erythroderma and alopecia, possibly linked to aminoaciduria.
Recognizing bamboo hair helps diagnose Netherton’s syndrome.
15 citations
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April 1970 in “PubMed” This letter describes a case of a 22-year-old woman with ichthyosis serpentina and related symptoms, suggesting it as a variant form of ichthyosis associated with bamboo hair, without necessarily including atopic features.
4 citations
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March 1999 in “International Journal of STD & AIDS” This report details a case of severe recurrent bacterial vaginosis in a woman with Netherton's syndrome.
3 citations
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June 2002 in “PubMed” This case report describes the diagnosis of Netherton's syndrome in two young sisters, attributing their serious erythrodermia, poor hair growth, and atopic conditions to this hereditary condition.
2 citations
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April 1970 in “Archives of Dermatology” This report discusses a case of ichthyosis serpentina, suggesting it as a variant of ichthyosis associated with bamboo hair, although atopy may not be a necessary component.