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Bariatric surgery improves ovulation rates in women with PCOS and obesity better than medical therapy.

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

Researchers found genes linked to hair growth cycles in Inner Mongolia cashmere goats, which could help understand and treat hair loss.

Hair loss in androgenic alopecia patients is linked to changes in certain genes that control cell growth and death.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Oral tofacitinib is a promising treatment for beard hair loss in alopecia areata.

Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.

Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Inactive hair follicle stem cells help prevent skin cancer.