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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Current treatments for alopecia show no significant long-term benefits.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Understanding hair follicle anatomy helps diagnose hair disorders.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Minoxidil shortens baldness from chemotherapy by 50.2 days without significant side effects.

The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Finasteride with oral contraceptive helps improve hair loss in premenopausal women.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Minoxidil helps hair growth by activating the β-catenin pathway.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

To diagnose hair loss, use a systematic approach including history, exams, and tests.

Alopecia Areata is an autoimmune condition often starting before age 20, with varied treatment success and a need for personalized treatment plans.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Careful planning and patient counseling can lead to excellent hair transplant results, often in one or two sessions.

The document concludes that good cosmetic outcomes in hair transplantation depend on the surgeon's artistic skill and careful planning.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

Combined minoxidil and tretinoin solution works as well as regular minoxidil for male hair loss.

Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.

No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.