research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice
Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.
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research Active Compounds With Medicinal Potential Found in Maxillariinae Benth. Representatives: A Review
Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
research Ketoconazole-P Aminobenzoic Cocrystal Exhibits a Potent Anti-Inflammatory Effect on the Skin of BALB/c Mice
The new cocrystal KET-PABA is a more effective and safe anti-inflammatory treatment for skin conditions in mice.
research Novel Aspects of Age-Protection by Spermidine Supplementation Are Associated with Preserved Telomere Length
Spermidine helps protect against aging by preserving telomere length.
research Promotional Effects of Sargassum Fusiforme Fractions on Hair Growth via In Vitro and In Vivo Models
Sargassum fusiforme extracts help promote hair growth.
research A Null Mutation in the Cystatin M/E Gene of Ichq Mice Causes Juvenile Lethality and Defects in Epidermal Cornification
A gene mutation in mice causes skin defects and early death.
research The Effects of Tea Polyphenolic Compounds on Hair Loss Among Rodents
Green tea compounds significantly increased hair regrowth in some mice.
research Unlocking The Potential Of Ganoderma Lucidum: Exploring The Efficacy Of Reishi Mushroom Extract In Promoting Hair Growth And Scalp Health
The study explores the efficacy of Ganoderma lucidum (reishi mushroom) extract in promoting hair growth and scalp health by inhibiting 5α-reductase isoform 2 (5αR2), a key enzyme involved in hair loss. Using an in vitro model with murine fibroblast BALB/3T3 cells pre-treated with testosterone, the researchers found that G. lucidum significantly inhibited 5αR2 expression, with effects comparable to known botanicals like Serenoa repens, Ajuga reptans, and the pharmaceutical finasteride. These findings suggest that G. lucidum could be effective in treating hair loss, though further in vivo studies are needed to confirm these results.
research Iatrogenic Male Infertility
Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.