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Targeted cancer therapies often cause serious skin problems that need careful management.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Myrtle has various health benefits and potential for medicine development.

Zinc is effective for treating various skin conditions, including warts and acne.

CDP is crucial for lung and hair follicle cell development.

Stem cell niches support, regulate, and coordinate stem cell functions.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Probiotic bacteria improved skin and hair health in aged mice.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.