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Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Bioprinting could improve wound healing but needs more development to match real skin.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.