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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Use minoxidil for hair loss treatment; assess results after 6 months.

The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.

Finasteride effectively blocks enzyme causing male pattern baldness.

Probiotic bacteria improved skin and hair health in aged mice.

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.

Pseudofolliculitis barbae is a chronic skin condition affecting mainly African American and Hispanic individuals, caused by shaving tightly curled hair, and managed by prevention and treatment but not curable.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

SCD1 is crucial for skin health and overall energy balance.

The EpiLight Hair Removal System removed about 60% of hair with some side effects, and more research is needed to confirm long-term effectiveness.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

Excision and laser techniques can effectively treat acne keloidalis nuchae.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

About 43% of people in Europe have had a skin condition in the past year, with fungal infections, acne, and eczema being the most common.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Early balding linked to higher heart disease risk.

Men with enlarged prostates often have more severe baldness.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.