research Transcriptomic Profiling of Frontal and Occipital Dermal Papilla Reveals Potential Role of TRPS1 in Androgenic Alopecia
TRPS1 loss in balding scalp areas contributes to hair loss in androgenic alopecia.
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research Role of Stem Cells in Skin Maintenance, Regeneration, and Repair: Focus on Epidermis and Pilosebaceous Units
The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
research Controlling MTORC1 Activity as a Novel Therapeutic Strategy for Managing Human Hair Growth and Pigmentation
Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
research Interspecies Variations in Response to Topical Application of Selected Zinc Compounds
Different zinc compounds cause varying levels of skin irritation in animals.
research Histology, Lectin Histochemistry, and Ultrastructure of Interdigital Gland in Crossbred Sheep
The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.
research Alopecia Areata Susceptibility Variant in MHC Region Impacts Expressions of Genes Contributing to Hair Keratinization and Is Involved in Hair Loss
A gene variant increases the risk of a type of hair loss by affecting hair protein production.
research Diversity of Trichocyte Keratins and Keratin-Associated Proteins
Hair and wool have diverse keratins and keratin-associated proteins.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein
Disulfide bonds make keratin in hair stronger and tougher.
research Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression
The substance AS101 can help hair grow by slowing down hair cell aging and boosting a hair growth protein.
research Chronological Aging of Human Hair Keratin Fibers
Hair ages as the cuticle wears down, especially beyond 1 meter from the root, affecting its strength and shine.
research Structural Hierarchy of Trichocyte Keratin Intermediate Filaments
Keratin proteins are crucial for hair growth and structure.
research Hair Follicle Transcriptome Profiles During the Transition from Anagen to Catagen in Cashmere Goat (Capra Hircus)
The transition from growth to regression in Cashmere goat hair follicles involves changes in expression of genes related to keratin and cell differentiation.
research Comparative Genomics of the Keratin-Associated Protein Gene Clusters in Human, Chimpanzee, and Baboon
KAP genes are crucial for hair development and show both shared and unique traits in humans, chimpanzees, and baboons.
research Expression of Novel Keratin-Associated Protein 5 Genes in the Cuticle Layer of Human Hair Follicles
The study found nine new hair protein genes in human hair follicles.
research Hair Follicle-Specific Keratins And Their Diseases
Only a few hair-specific keratins are linked to inherited hair disorders.
research Comedone Formation: Etiology, Clinical Presentation, and Treatment
Blocked hair follicles cause acne, and studying tiny early acne spots helps understand its severity.
research Wool Keratin-Associated Protein Genes in Sheep: A Review
Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
research The RAIG Family Member, GPRC5D, Is Associated With Hard-Keratinized Structures
GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
research Endocrine Controls of Keratin Expression
Hormones control keratin production in skin and hair.
research Lack of Androgen Receptor Transcriptional Activity in Human Keratinocytes
Human keratinocytes do not naturally respond to androgens.
research Local Structure of Human Hair Spatially Resolved by Sub-Micron X-Ray Beam
Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
research The Autoimmune Regulator (AIRE), Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Hair Keratinization in Health and Disease
Understanding intermediate filaments helps explain hair health and related diseases.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
research Metal Doped Keratin Film Standard for LA-ICP-MS Determination of Lead in Hair Samples
A new method accurately measures lead levels in hair to assess exposure.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Acid Phosphatase Distribution in the Wool Follicle: Fate of Organelles in Keratinized Cells
Keratinized wool cells still have some organelles like lysosomes and mitochondria.
research Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions
Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
research AP Collagen Peptides Improve Hair Growth and Quality by Promoting Human Hair Cell Proliferation and Keratin Synthesis
AP collagen peptides may help hair grow better and become stronger.