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Hamilton scale imprecise, hair shaft diameter decreases, stem cell transplant regrows hair, ECP ineffective for alopecia areata universalis.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Transplant patients face higher skin cancer risks due to immunosuppressive therapy, requiring careful skin health monitoring.

Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.

UVA1-light therapy successfully treated a child's skin condition, mycosis fungoides.

A woman's hair loss, resembling an autoimmune condition, improved after treatment, but requires ongoing checks due to potential serious associations.

Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Steven Kossard classified lymphocyte-related hair loss into four patterns, each linked to different types of baldness.

Every elderly patient had at least one skin condition, often linked to other diseases, highlighting the need for integrated skin and general healthcare in the elderly.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

Myc activation reduces skin stem cells by affecting cell adhesion.

Both mouse and rat models are effective for testing alopecia areata treatments.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

IL-6 from stem cells helps repair skin and grow hair.

Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.

p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

Terbinafine can cause hair loss.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.