June 2010 in “Seoul National University Open Repository (Seoul National University)” This article discusses the expression of vitamin D receptor in hair follicles and its role in alopecia, without presenting new findings; the authors highlight the involvement of Wnt/b-catenin signaling in hair growth.
12 citations
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September 2019 in “BioFactors” This study found that Ginkgolide B and bilobalide from Ginkgo biloba increased dermal papilla cell viability and promoted hair follicle growth in mink models by influencing signaling pathways.
July 2026 in “Journal of Zhejiang University (Medical Sciences)” This study found that adipose stem cell-derived nanovesicles promoted dermal papilla cell proliferation, migration, and anti-apoptotic effects in vitro and enhanced hair follicle cycle progression in mice, primarily through activation of the β-catenin signaling pathway.
November 2022 in “Journal of Investigative Dermatology” This study found that a lotion containing specific plant extracts significantly increased the number of anagen hairs and the anagen/telogen ratio in subjects with androgenetic alopecia after three months of use.
January 2026 in “Journal of Dermatological Science” This research observed that Salvianolic acid B (Sal B) significantly promoted hair regeneration in vivo and in vitro, outperforming minoxidil in a mouse model of androgenetic alopecia, by activating Wnt/β-catenin and mTORC2/Akt pathways and upregulating MMPs and MAPKs.
March 2024 in “Nutrients” This study found that Gynostemma pentaphyllum leaf hydrodistillate (GPHD) promoted hair growth in mice similarly to minoxidil and upregulated growth factor expression via the AKT/β-catenin signaling pathway, with damulin B identified as an active component contributing to these effects.
1 citations
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January 2025 in “Advances in Dermatology and Allergology” In this animal study, PRF enhanced the repair of chronic wounds in rats by reducing inflammation and promoting collagen deposition and new blood vessel formation, potentially through activating the Wnt/β-catenin signaling pathway.
January 2019 in “11th World congress for hair research” January 2010 in “Seoul National University Open Repository (Seoul National University)” This study investigated vitamin D receptor expression in normal hair follicles and those affected by alopecia areata, focusing on various markers using immunohistochemical staining.
4 citations
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June 2020 in “Cosmetics” This study reports that Broussonetia papyrifera extract significantly increased hair count over 12 weeks in a small clinical trial and promoted dermal papilla cell proliferation in vitro by regulating WNT-β-catenin and STAT6 pathways.
August 2024 in “Food Bioscience” This study reported that in laboratory conditions, a cell-free supernatant of Bifidobacterium longum BB536 promoted human dermal papilla cell proliferation and reduced damage and apoptosis caused by dihydrotestosterone, suggesting potential use as a preventative treatment for androgenic alopecia by modulating specific signaling pathways.
45 citations
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September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that deleting β-catenin in epidermis-specific VDR knockout mice did not prevent UVB-induced skin tumors, indicating β-catenin does not compensate for VDR's role in tumor suppression.
February 2024 in “Journal of medicinal food” This study reports that the β-catenin inhibitor tegatrabetan reduced hair growth and hair follicle numbers in mice, suggesting its potential as a model for developing new hair growth materials.
April 2017 in “Journal of Investigative Dermatology” This study identified that in mice, sweat gland development is directed by mesenchymal signals that suppress SHH-production, while in humans, this occurs through a BMP spike in embryonic development.
This study found that gels containing glycyrrhizic acid and aqueous Glycyrrhiza glabra extract significantly reduced underarm hair growth in terms of area, thickness, length, and number compared to their gel bases.
January 2016 in “Korean Journal of Pharmacognosy” This study found that Grateloupia elliptica extract may promote hair growth by activating wnt/b-catenin signaling and enhancing dermal papilla cell proliferation in rat and mouse models.
This article reviews the current understanding of the localization, characteristics, and potential markers of epidermal stem cells, and reports no new experimental results.
January 2023 in “Open Life Sciences” This study found that VEGFR-2 activation may play a role in hair follicle differentiation, proliferation, and apoptosis by co-expressing with several key proteins in normal human scalp skin.
April 2018 in “Journal of Investigative Dermatology” This study found that arrector pili muscles formed by Sonic Hedgehog signaling play a critical role in maintaining sympathetic nerve connections to hair follicle stem cells, influencing hair regeneration, with implications for hair loss treatments.
1 citations
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March 2022 in “Journal of Dermatological Science” This study concluded that overexpressing TERT and BMI1 in cultured human dermal papilla cells extended their lifespan and enhanced their ability to induce hair growth in mice.
19 citations
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April 2015 in “European Journal of Pharmacology” This study found that dihydrotestosterone (DHT) may shorten the hair growth cycle through mechanisms like cell-cycle arrest and β-catenin downregulation in rat hair follicle cells.
24 citations
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March 2018 in “Pigment Cell & Melanoma Research” This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.
24 citations
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January 2018 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses advances in molecular biology and genetics related to androgenetic alopecia and reports no new clinical results.
16 citations
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July 2021 in “Histopathology” This review discusses recent findings on molecular changes in cutaneous adnexal tumours and reports novel markers and pathways involved, highlighting the diverse oncogenic drivers and tumour suppressor alterations.
16 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.
8 citations
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September 2022 in “Biointerface Research in Applied Chemistry” This review examines the pharmacological potential of quinoline alkaloids from Cinchona bark for developing new drugs and cosmetics but reports no new findings.
January 2026 in “Theoretical and Natural Science” In this study, the authors explored the role of Lgr5+ hair follicle stem cells and their regulation through the Wnt/-catenin pathway, highlighting how precise modulation of this pathway is crucial for treating hair loss safely and effectively.
July 2024 in “Journal of Investigative Dermatology” Propolis extract can promote hair growth and increase keratin production.
January 2024 in “Brazilian Journal of Hair Health” This article discusses the role of androgens in androgenetic alopecia and suggests exploring additional causes and pathways involved, but reports no new clinical findings.
April 2019 in “Journal of Investigative Dermatology” This study found that bioelectric and biochemical signaling mechanisms coordinate collective cell movement during chicken feather bud morphogenesis, suggesting a potential new angle for research in skin development and wound healing.