8 citations,
October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
2 citations,
August 2022 in “Emergency medicine international” Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.
1 citations,
May 2022 in “Frontiers in Pharmacology” Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
June 2024 in “Journal of Allergy and Clinical Immunology” TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
March 2022 in “Journal of Investigative Dermatology” Discoid Lupus Erythematosus causes scalp plaques that can lead to hair loss, and antimalarial drugs are effective treatments.
June 2019 in “International journal of dermatology and venereology” The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
701 citations,
August 2014 in “Nature medicine” Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
328 citations,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
134 citations,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
112 citations,
January 2013 in “Experimental dermatology” Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
44 citations,
October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
24 citations,
December 2018 in “Inflammation and Regeneration” Phospholipase A2 enzymes play key roles in skin health and disease.
3 citations,
July 2023 in “Biomolecules” B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.
1 citations,
March 2023 in “Aggregate” A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
1 citations,
May 2012 in “Hair transplant forum international” Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
August 2024 in “Indian Journal of Skin Allergy” Stem-cell therapy shows promise for skin conditions but needs more research.
April 2024 in “International journal of molecular sciences” Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
February 2024 in “Veterinary sciences” Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.
September 2023 in “Medicine” The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
January 2023 in “Applied sciences” Gefitinib and Sasam-Kyeongokgo together significantly reduce cancer growth and improve immune response in mice.
January 2023 in “Annals of dermatology/Annals of Dermatology” A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.
52 citations,
December 2014 in “Journal of Dermatological Science” Apremilast may help treat hair loss in alopecia areata.
45 citations,
June 2018 in “Frontiers in immunology” MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
24 citations,
August 2021 in “Biologics” Stem cell therapy shows promise in improving burn wound healing.
15 citations,
January 2022 in “Immune Network/Immune network” New targeted immunotherapies are improving treatment for inflammatory skin diseases.
10 citations,
August 2022 in “International Journal of Molecular Sciences” Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
9 citations,
April 2021 in “Frontiers in Immunology” Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
6 citations,
August 2022 in “Science immunology” Foxn1 gene regulation is crucial for thymus development but not for hair growth.
5 citations,
February 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.