March 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” This study found that a chitosan, chondroitin sulfate, and hyaluronic acid scaffold improved wound healing in rats by promoting immune-stromal interactions, reducing inflammation, and supporting tissue regeneration with ~91% wound closure by day 17 compared to ~63% in controls.
2 citations
,
January 2000 in “Journal of Toxicologic Pathology” This study identified a single autosomal recessive gene responsible for hypotrichosis in a mutant rabbit strain, affecting hair growth and causing epidermal and hair follicle abnormalities.
July 2026 in “Plastic & Reconstructive Surgery Global Open” This study found that intradermal injections of plant-derived exosomes in adults with early-stage alopecia increased stem cell activity, activated Wnt signaling pathways, and reduced certain immune cell populations, providing insights into their role in hair follicle regeneration and suggesting potential for hair restoration therapy.
7 citations
,
March 2022 in “International Journal of Molecular Sciences” This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.
84 citations
,
June 2013 in “Stem Cells Translational Medicine” This review discusses strategies for regenerating cutaneous nerve function in burn patients and highlights the potential role of autologous skin-derived adult stem cells in improving sensory recovery, but reports no new experimental findings.
64 citations
,
November 2012 in “EMBO reports” This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.
32 citations
,
January 2000 in “Skin pharmacology and physiology” In this study, procyanidin B-2 and C-1 were found to promote hair growth by selectively inhibiting protein kinase C, supporting their potential use for hair-growing activity.
24 citations
,
May 2006 in “Proceedings of the National Academy of Sciences of the United States of America” This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.
24 citations
,
May 2017 in “PubMed” This review evaluates biotin's popularity and its purported benefits for hair improvement but finds no clinical evidence supporting its efficacy.
9 citations
,
June 1999 in “Journal of Investigative Dermatology” This study observed hair-specific transcription of a reporter gene in transgenic mice, with increased expression after dexamethasone and ultraviolet B treatment.
9 citations
,
February 1981 in “Australian journal of biological sciences” This study found that crossbred lambs fed liquid diets with reconstituted cow's milk initially grew wool without crimp, with crimp resuming two weeks post-weaning.
5 citations
,
May 2024 in “Molecules” This study found that glycyrrhetinic acid, derived from licorice, may help alleviate acne symptoms by regulating lipid synthesis and inflammatory responses through multiple pathways, as observed in both in vitro and in vivo settings.
2 citations
,
June 2024 in “Archives of Dermatological Research” In this study, researchers compared three treatments for stable vitiligo and found that a combination of follicular cell suspension and mini punch grafting resulted in significantly better re-pigmentation after six months compared to using either method alone.
December 2020 in “Nigerian journal of animal production” This study found that dexamethasone may induce diabetes in albino rats and Annona muricata methanolic bark extract resulted in significantly reduced blood sugar levels in dexamethasone-induced diabetic rats.
September 2022 in “Journal of pharmaceutical sciences” This study found that adding hydroxypropyl cellulose to minoxidil formulations significantly increased scalp retention and penetration compared to other formulations, potentially leading to reduced application frequency and improved efficacy.
3 citations
,
October 2024 in “International Journal of Molecular Sciences” This study found that subthermal CRET treatment increased keratinocyte proliferation and modulated cytokine production, affecting the inflammatory response in human keratinocytes through EGFR and ERK1/2/NF-κB pathways.
1 citations
,
April 2022 in “F1000Research” This study found that pediatric cancer patients at Muhimbili National Hospital commonly experienced adverse drug reactions during chemotherapy, despite drug prescribing patterns aligning with essential medicine lists.
April 2017 in “Journal of Dermatological Science” In this study, researchers found that in adult mice, new hair follicles with pigmentation can regenerate from the epidermis after skin wounding, aided by melanocyte stem cells moving from nearby existing hair follicles.
1 citations
,
October 2022 in “International journal of endocrinology” This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.
59 citations
,
January 2005 in “Endocrine Journal” This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.
30 citations
,
October 1999 in “Differentiation” This study found that expression of certain mutant keratin genes in mice led to severe alopecia, suggesting a similar mechanism could cause hair loss in humans.
21 citations
,
February 2023 in “Pharmaceuticals” This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
18 citations
,
January 2009 in “Experimental Dermatology” This study proposes that mammalian target of rapamycin (mTOR) may connect various signaling pathways in hair follicle tumor formation, offering a potential unified model for understanding these tumors.
13 citations
,
October 2007 in “Bulletin of the Korean Chemical Society” This article reviews mollugin's reported biological activities, including its potential for various therapeutic and cosmetic applications such as anti-tumor effects and hair growth stimulation, but presents no new experimental data.
4 citations
,
October 2024 in “International Journal of Molecular Sciences” This study found that chitosan nanoparticle-encapsulated Cordyceps militaris significantly reduced inflammation and oxidative stress in particulate matter-exposed mice, suggesting potential use for managing lung inflammation.
1 citations
,
August 2025 in “Molecules” This review synthesizes research on hederagenin's anticancer and anti-inflammatory potential, emphasizing chemical modifications to enhance its bioactivity, but reports no new experimental findings.
1 citations
,
December 2023 in “Skin Research and Technology” This study reported successful repigmentation of perioral vitiligo using upper hair follicle transplantation combined with a 308 nm excimer laser, without undesirable hair growth in the treated areas, offering a potential approach for treating vitiligo cases unresponsive to traditional melanocyte transplantation.
1 citations
,
May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This paper reviews several dermatological studies, including findings on hair growth, skin damage, bullous pemphigoid, and psoriasis treatments, and reports no new clinical results.
January 2026 in “Journal of Materials Chemistry B” This study concluded that the KNPs@M/G microneedle system offers a promising strategy for treating radiation-induced skin injury by promoting antioxidative, anti-inflammatory, and regenerative effects.
December 2024 in “Drug Discoveries & Therapeutics” This study investigated using baricitinib-loaded mesenchymal stem cell exosomes injected locally in an alopecia areata mouse model and found that this method improved hair regrowth better than baricitinib or exosomes alone, potentially offering a new therapeutic approach for treating alopecia areata.