33 citations,
December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
26 citations,
February 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” An enzyme other than TNAP might be responsible for vitamin B-6 metabolism in the skin.
23 citations,
September 2015 in “International Journal of Molecular Medicine” Activating ER-β, not ER-α, improves skin cell growth and wound healing.
20 citations,
May 2016 in “Journal of Cosmetic Dermatology” Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.
14 citations,
March 2017 in “Brain research” Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.
Alopecia areata patients have higher levels of certain immune receptors, suggesting new treatment possibilities.
227 citations,
January 1998 in “Journal of Endocrinology” Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
81 citations,
June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
81 citations,
July 2012 in “Translational Psychiatry” Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
76 citations,
May 2011 in “Cell death and differentiation” A20 protein is crucial for normal skin and hair development.
36 citations,
December 2002 in “Experimental dermatology” Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.
31 citations,
November 2016 in “Cell Reports” Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
25 citations,
May 2016 in “Progress in Biophysics & Molecular Biology” R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.
22 citations,
March 2017 in “Scientific reports” Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
20 citations,
December 2013 in “Journal of Dermatology” UV-B light increases inflammation-related substances in acne-related skin cells.
18 citations,
February 2012 in “Experimental Dermatology” No link found between specific genes and female pattern hair loss.
18 citations,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
13 citations,
April 1994 in “Journal of Investigative Dermatology” Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
9 citations,
June 2019 in “Archives of Dermatological Research” Both topical calcipotriol and narrowband UVB improved alopecia, but combining them didn't enhance the effect on hair loss severity, despite higher vitamin D3 levels.
9 citations,
August 2014 in “European journal of ophthalmology” PGFb>2αb> receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.
7 citations,
January 2019 in “Australasian Journal of Dermatology” A genetic marker linked to a type of hair loss was found in most patients studied.
5 citations,
January 2013 in “Cells Tissues Organs” Activin B helps start and grow hair follicles in mice.
5 citations,
January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New steroids were effective in blocking male hormone receptors in hamster prostates.
4 citations,
August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
April 2023 in “Clinical theriogenology” The dog's skin condition improved after removing a tumor that was causing hormone imbalances.
July 2022 in “Research Square (Research Square)” Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.
February 2016 in “Evidence Based Women Health Journal (Online)” Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.
December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.