7 citations
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June 2024 in “Skin Research and Technology” Combining treatments significantly reduces dark circles and wrinkles better than nanofat alone.
3 citations
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January 2023 in “Journal of Cosmetic Dermatology” This study found that combining Fractional CO2 laser with platelet-rich plasma led to better improvement in vitiligo treatment compared to platelet-rich plasma alone, based on patient satisfaction and lesion size reduction.
3 citations
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February 2021 in “Medical journal, Armed Forces India” In this observational study, the combination of PRP and 5% minoxidil was more effective than minoxidil alone in promoting hair growth in men with androgenetic alopecia.
1 citations
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January 2022 in “Journal of Cutaneous and Aesthetic Surgery” This study found that adding platelet-rich plasma to 5% minoxidil treatment improved hair growth outcomes in patients with androgenetic alopecia compared to minoxidil alone.
1 citations
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September 2015 in “MVP journal of medical science” In this study, the combination of minoxidil, azelaic acid, and tretinoin showed no significant advantage over minoxidil alone for treating androgenetic alopecia.
September 2026 in “Frontiers in Veterinary Science” This study found that the novel VG111 formulation alone healed canine wounds nearly twice as fast as the standard povidone–iodine treatment, achieving complete healing in 25 days compared to up to 50 days.
September 2026 in “Russian Journal of Skin and Venereal Diseases” In this study, photodynamic therapy combined with platelet-rich plasma showed potential for greater efficacy than photodynamic therapy alone in treating androgenic alopecia, with both approaches improving hair density without serious side effects.
August 2026 in “Journal of Maxillofacial and Oral Surgery” This study investigated treatments for male androgenetic alopecia, finding that combining injectable platelet-rich fibrin (i-PRF) with microneedling increased hair growth more effectively than i-PRF alone according to questionnaires and photographic assessments.
September 2025 in “Journal of Maxillofacial and Oral Surgery” This study found that combining PRP with concentrated growth factors was more effective than PRP alone in promoting hair regrowth for patients with androgenetic alopecia.
March 2025 in “Egyptian Journal of Animal Health” This study observed that supplementing buffalo calves with a mineral mixture alone or combined with Nigella sativa seeds improved skin conditions and hematobiochemical parameters in calves suffering from parakeratosis, which is primarily due to zinc deficiency.
November 2024 in “Journal of Investigative Dermatology” Ursolic and shikimic acid together boost hair growth better than alone.
This meta-analysis found that platelet-rich plasma therapy significantly increased hair density in androgenic alopecia, with stand-alone PRP showing notable improvements, but the benefits of combining PRP with other therapies remain uncertain.
October 2014 in “Journal of skin and stem cell” This study found that combining Elidel with tretinoin was more effective for treating alopecia areata than using Elidel alone.
April 2011 in “Global journal of health science” In this study, spironolactone alone and combined with oral contraceptive pills significantly reduced hair shaft diameter in women with hirsutism, with the combined treatment showing the most substantial improvement.
November 2007 in “Neuro-chirurgie/Neurochirurgie” This study reported that treatment with cyproterone acetate alone and then with incremental estrogen doses induced mild feminizing effects in late-pubertal trans-girls, with further feminization observed after adding estrogen.
October 2006 in “Urology” Combination therapy with Finasteride is more effective than alpha-blocker alone for BPH symptoms in small prostate volume.
June 1982 in “Revista Colombiana de Obstetricia y Ginecología” This article discusses treatments for androgenic manifestations using cyproterone acetate alone or with estrogens, but it does not provide new clinical results.
April 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study concluded that combining platelet-rich plasma with low-level light therapy was more effective than combining it with minoxidil or using light therapy alone for treating androgenetic alopecia.
January 2022 in “The Egyptian Journal of Hospital Medicine” This study found that combining fractional CO2 laser with 5% minoxidil was more effective than using 5% minoxidil alone for treating male androgenetic alopecia, and no serious adverse effects were identified.
July 2021 in “Indian journal of drugs in dermatology” In this study, the combination of intradermal meso-solution and topical 5% minoxidil significantly increased hair re-growth in men with androgenetic alopecia compared to minoxidil alone.
April 2021 in “International Journal of Research in Dermatology” This study found that treating male pattern androgenetic alopecia with a combination of topical minoxidil and finasteride resulted in better outcomes for hair growth and density compared to using minoxidil alone.
October 2019 in “International Journal of Research in Dermatology” This study found that combining topical minoxidil with oral spironolactone improved hair loss outcomes in women with female pattern hair loss when compared to minoxidil alone, but benefits plateaued after 6 months.
79 citations
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September 2018 in “Dermatologic therapy” This study found that treatment with oral tofacitinib, alone or with other therapies, was associated with clinical improvement in most patients with recalcitrant lichen planopilaris.
44 citations
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May 2006 in “The Journal of the American Animal Hospital Association/Journal of the American Animal Hospital Association” This study observed that combination therapy with prednisolone and azathioprine provided similar outcomes to prednisolone alone for treating pemphigus foliaceus in dogs, with over half achieving remission and significant improvement in another 25%.
20 citations
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June 2019 in “Archives of dermatological research” In this study, combination therapy with DPCP and anthralin promoted hair regrowth in 40.62% of alopecia areata patients who were unresponsive to DPCP alone, with response improving over longer treatment durations.
20 citations
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January 2013 in “Evidence-based complementary and alternative medicine” This study found that TGPC plus CGT was more effective than CGT alone in reducing alopecia areata severity in children over 12 months, with similar safety profiles.
17 citations
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February 2001 in “Journal of the American Academy of Dermatology” This case report suggests that lithium, either alone or with haloperidol, may induce skin changes resembling follicular mycosis fungoides.
11 citations
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January 2024 in “Gynecological Endocrinology” This narrative review on inositol use in PCOS treatment found positive results for myo-inositol alone and effective outcomes for a myo-inositol/D-chiro inositol combination at a 40:1 ratio, suggesting further research on other combinations like 66:1 to 100:1.
10 citations
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January 2020 in “Acta Neurobiologiae Experimentalis” This study found that valproic acid and crocin, alone or together, significantly increased the expression levels of neurotrophic factors in rat-derived epidermal neural crest stem cells, suggesting therapeutic potential for neurological disorders.
9 citations
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February 2021 in “Evidence-based Complementary and Alternative Medicine” This study reported that Longdan Xiegan decoction is more effective than conventional western medicine alone in treating eczema, but the evidence quality was generally low, highlighting the need for further studies.