42 citations
,
February 2000 in “Journal of Investigative Dermatology” This study found that Gelatinase A activity is linked to the absence of type VII collagen during human fetal skin development, indicating its role in remodeling the basement membrane zone.
33 citations
,
August 2000 in “Experimental Cell Research” August 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This review paper provides a comprehensive overview of Dutasteride, detailing its pharmacological properties, mechanisms, and therapeutic applications, particularly for androgenetic alopecia and benign prostatic hyperplasia, and discusses its potential use in prostate cancer prevention and transgender medicine.
68 citations
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January 2022 in “International Journal of Molecular Sciences” This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.
14 citations
,
May 2005 in “Steroids” This study describes the synthesis of finasteride from 4-androstene-3,17-dione in a seven-step process with an overall yield of 18.6%.
6 citations
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July 2007 in “Organic Process Research & Development” This study optimized the reaction conditions for the stereoselective hydrogenation of a compound used in manufacturing finasteride and dutasteride, improving the selectivity for the desired isomer.
5 citations
,
January 2022 in “Proceedings of the Pakistan Academy of Sciences B Life and Environmental Sciences” This review discusses the role of nanoparticles in cancer diagnosis and treatment and outlines their potential to improve outcomes by reducing systemic toxicity and overcoming multidrug resistance, though it reports no new clinical results.
4 citations
,
January 1998 in “Heterocycles” Researchers made two new compounds that could be used for medicine.
2 citations
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December 2008 in “Journal of Chemical Crystallography” This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.
December 2025 in “Journal of Composites and Compounds” In this review, researchers explored the design of composite biomaterials for immunomodulation and their potential to influence immune cell behavior, which could be leveraged for treating diseases like cancer and improving tissue regeneration, while also addressing translational challenges such as biocompatibility and safety.
January 2025 in “The World Journal of Men s Health” In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.
This review highlights the therapeutic potential of Hibiscus rosa-sinensis, detailing its significant medicinal value for treating various conditions such as wounds, infections, and diabetes, attributed primarily to its bioactive compounds like flavonoids and tannins.
42 citations
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June 2021 in “Pharmaceutics” This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.
20 citations
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September 2018 in “Journal of colloid and interface science” This study found that keratin derivatives with functionalized thiol groups improved binding to both natural and bleached hair fibers, suggesting a promising strategy for enhancing keratin's durability in hair repair.
3 citations
,
June 2018 in “The New England Journal of Medicine” This case report describes a 45-year-old woman with persistent fatigue and confusion following hypertension treatment, who developed pulmonary embolism four weeks later.
1 citations
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January 2024 in “Asian Journal of Microbiology Biotechnology and Environmental Sciences” This review examines the growing global demand for diverse tea products, highlighting their health benefits and the economic challenges tea-producing countries face, while also exploring the rise of tea-based nutraceuticals, confectionery, toiletries, and cosmeceuticals.
June 2013 in “D-Scholarship@Pitt (University of Pittsburgh)” This article discusses the development of an interactive workbook by OCCAM to help cancer patients communicate their use of complementary and alternative medicine with healthcare providers and reports no clinical results.
72 citations
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March 2023 in “Biomolecules” This study reviewed the use of dupilumab, beyond its approved indications for atopic dermatitis and prurigo nodularis, and found effective treatment reports for various chronic inflammatory skin diseases such as bullous autoimmune diseases, eczema, and alopecia areata, highlighting its broad potential in dermatology.
16 citations
,
November 2020 in “Research Square (Research Square)” In this study, early treatment with nitazoxanide, ivermectin, or hydroxychloroquine, combined with azithromycin, was associated with reduced hospitalizations, respiratory complications, and deaths in early-stage COVID-19 patients compared to untreated controls.
11 citations
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November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that early treatment with azithromycin and either nitazoxanide, ivermectin, or hydroxychloroquine in COVID-19 patients may reduce viral shedding, symptom duration, and respiratory complications compared to untreated patients.
11 citations
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March 2018 in “Protoplasma” In this laboratory study, procyanidin B2 inhibited early plant growth and biochemical responses in wheat seedlings treated with lipopolysaccharides from Azospirillum brasilense, suggesting that plant response activation requires LPS recognition by plant cells.
8 citations
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June 2022 in “International Journal of Molecular Sciences” This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.
4 citations
,
October 2023 in “Journal of clinical medicine” This meta-analysis found that women with polycystic ovary syndrome have over a 2.5-fold higher risk of depression compared to healthy women.
3 citations
,
December 2018 in “Biomedical and pharmacology journal/Biomedical & pharmacology journal” This study found that compound 3 derived from aza-bicyclo-carboxylic acid may exert a cardioprotective effect by reducing infarction area in myocardial ischemia-reperfusion injury, potentially involving A1-adenosine receptor activation and changes in cAMP levels.
1 citations
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April 2025 in “Journal of Clinical Medicine” This review reports that alopecia areata negatively affects sexual functioning, highlighting the need for further research due to limitations in current study sizes and populations.
1 citations
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October 2018 in “Infectious diseases in clinical practice” This case report documents what may be the second reported instance of azithromycin-induced agranulocytosis, highlighted by a sudden drop to zero in absolute neutrophil count in a 67-year-old man.
March 2026 in “Indian journal of veterinary and animal sciences research.” In this study, a five-year-old Labrador with pemphigus, characterized by erythematous lesions and confirmed through cytology, was successfully treated with a six-week regimen of oral immunosuppressive azathioprine and supportive medications, resulting in total recovery.
December 2023 in “International Journal of Dermatology” This study found an increased risk of asthma and allergic rhinitis in individuals with hidradenitis suppurativa.
November 2022 in “Piretc” This analysis of the innovation process in Azerbaijan's oil and gas industry suggests that information technology plays a crucial role in achieving sustainable development by integrating new scientific knowledge with technology.
29 citations
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May 2025 in “Polymers” This study systematically examines how smart biomaterials used with DLP technology can enhance bioprinting in tissue engineering and regenerative medicine, while also identifying current challenges and future research needs.