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GlossaryRosiglitazone (Avandia)

medication for type 2 diabetes that improves insulin sensitivity

Rosiglitazone, also known by the brand name Avandia, is a medication used to manage type 2 diabetes by improving insulin sensitivity. It belongs to a class of drugs called thiazolidinediones, which work by activating PPAR-gamma receptors to enhance the body's response to insulin, thereby lowering blood sugar levels.

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research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review

343 citations, December 2008 in “Endocrine Reviews”

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

research Contemporary Medical Therapy for Polycystic Ovary Syndrome

31 citations, September 2006 in “International journal of gynaecology and obstetrics”

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Impact of Treatment with Rosiglitazone or Metformin on Biomarkers for Insulin Resistance and Metabolic Syndrome in Patients with Polycystic Ovary Syndrome

research Impact of Treatment with Rosiglitazone or Metformin on Biomarkers for Insulin Resistance and Metabolic Syndrome in Patients with Polycystic Ovary Syndrome

19 citations, March 2007 in “Journal of diabetes science and technology”

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

research Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome

97 citations, July 2006 in “Dermatologic therapy”

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

research Primary Cicatricial Alopecia: Treatment Approaches and Classification

95 citations, November 2016 in “Journal of The American Academy of Dermatology”

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

research Dermatology of Androgen-Related Disorders

67 citations, July 2006 in “Clinics in Dermatology”

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

research Insulin-Lowering Medications in Polycystic Ovary Syndrome

39 citations, September 2000 in “Obstetrics and Gynecology Clinics of North America”

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

research Obesity and Polycystic Ovary Syndrome

28 citations, November 2007 in “Medical Clinics of North America”

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

research Pharmacologic Treatment of Polycystic Ovary Syndrome

21 citations, January 2003 in “Seminars in reproductive medicine”

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite

3 citations, March 2017 in “Regulatory toxicology and pharmacology”

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

research Characterization And Neural Differentiation In Vitro Of Stem Cells From Human Deciduous Tooth Pulp

1 citations, November 2015

Dental pulp stem cells might not reliably become neurons.

research Reporting on Adverse Clinical Events

July 2017 in “Clin-Alert”

Different medications can cause serious side effects in some people.