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Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Natural products like propolis are causing more skin allergies, and certain skin treatments and medications have various side effects and risks.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Hibiscus rosa-sinensis leaf extract helps hair grow longer and faster.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

New nanocomposites with copper show promise for healing burn wounds and regenerating skin.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Minoxidil and finasteride effectively treat hair loss.

The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

Tiny needles with valproic acid can effectively regrow hair.

Different factors affect where drugs are absorbed in the small intestine, which is important for effective medication use.

Malnutrition severely harms growth and development in young baboons.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

New treatments for acne scars are safer and more effective because we understand the causes better.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Mood stabilizers can cause serious skin reactions; careful monitoring and immediate treatment are crucial.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.