5 citations,
June 2022 in “Frontiers in immunology” Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.
3 citations,
July 2021 in “Aesthetic Plastic Surgery” PHAT may improve hair growth better than PRP alone.
November 2022 in “CARDIOMETRY” A group has developed therapies that show promise for treating cancer and various other conditions.
11 citations,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
1 citations,
January 2010 in “Elsevier eBooks” Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.
79 citations,
October 2015 in “Journal of Dermatological Treatment” Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.
6 citations,
October 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Rice bran extract boosts melanin production in hair follicles.
5 citations,
August 2018 in “Experimental Dermatology” The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.
2 citations,
March 2009 in “Journal of the American Academy of Dermatology” Many research paper titles in dermatology journals lack scientific precision.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
May 2004 in “Pediatric Dermatology” Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
56 citations,
November 2016 in “Aesthetic surgery journal” The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.
39 citations,
October 2015 in “Case Reports” Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.
18 citations,
May 2013 in “Cutaneous and Ocular Toxicology” The cancer drugs bortezomib and lenalidomide cause skin side effects in many patients.
12 citations,
June 2019 in “Clinics in dermatology” PRP shows promise for skin rejuvenation but needs more research.
April 2007 in “Nature Clinical Practice Urology” Finasteride lowers PSA levels about the same whether taken at 1 mg or 5 mg daily.
August 2023 in “Journal of Cosmetic Dermatology” Exosomes from hair papilla cells and the Chinese medicine Liao Tuo Fang can potentially promote hair growth and could be used to develop hair growth drugs.
January 2020 in “Journal of translational science” 29 citations,
February 2020 in “Transfusion and Apheresis Science” Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
November 2022 in “Frontiers in Medicine” This systematic review assessed the efficacy of platelet-rich plasma (PRP) in treating alopecia areata (AA) and primary cicatricial alopecias (PCAs) by analyzing 32 studies with 621 AA patients and 19 PCA patients. PRP showed promising results in AA, especially in mild cases, with better efficacy than placebo and similar efficacy to intralesional triamcinolone acetonide (TA). PRP also had benefits as an adjunctive treatment. However, its efficacy in PCAs was less clear due to limited studies and variable responses. The review emphasizes the need for more high-quality, randomized controlled trials to confirm PRP's therapeutic potential in these conditions.
79 citations,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
January 2021 in “Türk plastik cerrahi dergisi” The study evaluated the efficacy and safety of activated platelet-rich plasma (aPRP) in treating androgenetic alopecia (AGA) in 40 male patients, with 35 completing the study. Patients received 5 sessions of aPRP injections, spaced 15 days apart, with aPRP injected into one half of the scalp and placebo in the other half. Results at 1 and 3 months follow-up showed a significant increase in hair count, hair density, and anagen/telogen ratio in the aPRP-treated areas compared to placebo. The study concluded that aPRP is a safe and effective treatment for AGA, with a stabilizing effect on hair fall and potential to prevent progression of alopecia in its early stages. No major side effects were reported, but further studies with larger cohorts and longer follow-up periods were recommended.
16 citations,
October 2015 in “Tissue Engineering Part C-methods” A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
7 citations,
May 2021 in “Frontiers in Pharmacology” The systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) in treating female androgenic alopecia (FPHL) and included 42 studies with 1,569 cases, of which 776 were female participants. PRP showed positive responses and improvements in hair density compared to baseline and placebo, with minimal adverse effects such as mild pain and bruising at injection sites. The study concluded that PRP is a promising treatment for FPHL, though further high-quality randomized controlled trials are needed to confirm its efficacy due to considerable heterogeneity and publication bias.
1 citations,
April 2023 in “Biomolecules” Fermented papaya and mangosteen in hair care products helped prevent hair loss and improve hair thickness.
2 citations,
January 2022 in “International Journal of Medical Sciences” Kartogenin may help treat hair loss by promoting hair growth and extending the hair growth phase.
2 citations,
July 2023 in “International Journal of Molecular Sciences” BFNB could be a promising treatment for hair growth.
August 2023 in “Bioengineering” Bioprinting could greatly improve health outcomes but faces challenges like material choice and ensuring long-term survival of printed tissues.
January 2022 in “Pastic and aesthetic research” PRP helps skin regeneration but needs standardized testing for consistent results.