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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Researchers identified genes that may affect hair growth in Cashmere goats.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Exosomes can help promote hair growth and may treat hair loss.

COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.

Genes linked to wool fineness in sheep have been identified.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

SkQ1 antioxidant improved health and lifespan in mice.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.

Innovative biomaterials show promise in healing chronic diabetic foot ulcers.

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.

DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.

Overactive Wnt signaling in mouse skin stem cells causes acne-like cysts and shrinking oil glands, which some treatments can partially fix.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Metabolites and diet affect hair growth cycles in cashmere goats.

Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Melanoblasts migrate to the skin using various pathways, and understanding this process could help with skin disease research.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Notch signalling helps skin cells differentiate and prevents tumors.

Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.