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This review outlines the role of dermal fibroblasts in wound healing and highlights their potential in developing new cellular therapies, but reports no new clinical results.

In this study, autologous fibroblasts combined with keratin gel were reported to effectively and safely improve tear trough deformities up to 24 months post-injection, with no severe adverse effects observed.

RCS-01 is safe and may help rejuvenate aging skin.

This study found that a complex filling material made from autologous skin fibroblasts and hair keratin significantly improved the appearance of facial wrinkles, suggesting potential for clinical cosmetic applications.

This article reviews autologous cell therapy for facial wrinkles, detailing the use of LaViv and its adverse events, but reports no new clinical results.

Fibroblasts can be turned into melanocytes for potential skin treatments.

This study developed a rapid, cost-effective three-dimensional skin equivalent model using human dermal fibroblasts, collagen, and hair follicles, which closely resembles natural human skin and can be used for autologous transplantation.

This article discusses the potential use of human hair follicular stem cells combined with platelet-rich plasma for androgenetic alopecia, focusing on the regenerative processes involved, but reports no new clinical results.

This study developed a 3D skin model with immune and endothelial cells, which may enhance understanding of skin biology and diseases due to its closer approximation to native skin.

In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.

This study found that an injectable material derived from hair shows good biocompatibility and promotes dermal thickness in pigs, suggesting potential as a new soft tissue filling agent.

This study concluded that combination therapies often yield better results for treating atrophic post-acne scars than single treatments.

This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice were slightly less effective, yet had comparable therapeutic effects on wound healing compared to non-diabetic controls.

This article reviews existing research on the treatment of alopecia areata using growth factors and microneedling, reporting that these methods show promise in promoting hair growth without major adverse effects, but emphasizes the need for additional large-scale studies to confirm their efficacy and safety.

This study reviewed cases of filler-induced alopecia and found that hyaluronic acid injections were most commonly associated with this condition, highlighting that hyaluronidase treatments can rapidly restore hair density, while alternative interventions need further exploration.

In this research, the authors identify coordinated mechanical forces as crucial for hair follicle development in mammals, with contractile, proliferative, and proteolytic activities facilitating the formation and sectioning of epithelial structures crucial for forming a functional tissue.

This study found that an autologous keratin and fibroblast tissue filler was effective for correcting moderate-severe depressed scars, with the majority of patients experiencing excellent improvement and no severe complications.

This study reports that autologous micrografting may effectively treat stretch marks by promoting extracellular matrix remodeling and enhancing fibroblast activity, potentially expanding therapeutic options for this condition.

This study found that combining microfocused ultrasound with autologous blood cell factors significantly improved skin rejuvenation compared to using microfocused ultrasound alone.

Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.

Platelet-rich plasma may help with wound healing, hair growth, and skin rejuvenation, but more research is needed to prove its effectiveness.

This review examines non-surgical methods for rejuvenating the periorbital area and highlights the growing role of platelet-rich plasma, but it reports no new clinical findings.

This study developed a humanized scalp model in mice which demonstrated that transplanted cultured human hair follicle dermal cells contributed to the restoration of damaged hair follicles.

This study found that murine vibrissa hair follicle stem cells can differentiate into corneal epithelial-like cells in vitro when cultured with limbus-specific microenvironmental factors.

This study reports encouraging results in treating androgenetic alopecia by combining injectable PRF and PDO thread insertion on the scalp.

This study found that murine vibrissa hair follicle stem cells can be differentiated into corneal epithelial-like cells in vitro using limbus-specific microenvironmental factors, suggesting a potential therapeutic source for ocular surface disorders.

PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.

This study found that autologous platelet-rich plasma increased hair growth potential by enhancing dermal papilla cell proliferation and stimulating key signaling pathways in both cell cultures and mice models.

Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.

This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.