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This article reviews existing research on the treatment of alopecia areata using growth factors and microneedling, reporting that these methods show promise in promoting hair growth without major adverse effects, but emphasizes the need for additional large-scale studies to confirm their efficacy and safety.

This study observed that autologous bone marrow derived mononuclear cells and follicular stem cells were both safe and effective for improving resistant alopecia areata and androgenetic alopecia, with no serious adverse events.

In this case report, two young women with female pattern hair loss experienced significant hair regrowth without adverse effects after six months of treatment with bone-marrow-derived mesenchymal stem cells and their extracellular vesicles, suggesting potential for this approach when conventional treatments fail.

This systematic review found that both cellular and acellular stem cell-based therapies are safe and able to improve hair regeneration and density in patients with androgenic alopecia, although some results may be temporary.

This study demonstrated that autologous mesenchymal stem cells from hair follicles, when combined with a novel gelatin-based hydrogel, showed promising osteogenic potential and could offer a non-invasive alternative for bone regeneration.

This study suggests that mesenchymal stem cell-induced dermal papilla-like tissues can generate new hair follicles in mice, indicating potential for developing hair cell therapy using stem cells.

This study found that gelatin sponges used as scaffolds in rats with deep wounds and periosteal defects enabled regeneration of diverse tissue types, including periosteum, skin, and appendages, highlighting the role of vascular niche formation.

In this study using diabetic rat models, the combination of AMD3100 and low-dose FK506 reduced wound healing time and improved microcirculation in diabetic foot ulcers, indicating a promising new systemic therapy.

This study found that combining adipose-derived mesenchymal stromal cells with meglumine antimoniate reduced lesion size and parasite load in mice with leishmaniasis, suggesting potential for improved treatment.

This study found that hair follicle mesenchymal stem cells are similar to bone marrow stem cells in most characteristics, but differ in their adipogenic and osteogenic differentiation capabilities, suggesting they may be a suitable source for adipogenesis research.

This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence.

This study found that while MSC concentration in BMCs correlates with total cell counts, cellularity does not indicate high MSC content.

This study demonstrated that pharmacologically mobilizing endogenous bone marrow stem cells with AMD3100 and low-dose FK506 can enhance liver regeneration and improve liver function in rats after extensive hepatectomy.

This study discusses treatment approaches for refractory Asherman syndrome, highlighting the potential role of CD133+ bone marrow-derived stem cells in conjunction with hysteroscopy for endometrial regeneration and improved pregnancy outcomes.

This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.

This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.

This review suggests that stem cells might be a promising addition or alternative to standard treatments for androgenic alopecia, but larger studies are needed to confirm these findings.

In this study, researchers assessed the efficacy of Trichosera® hair serum, containing mesenchymal stromal cells conditioned media, among 40 healthy Indian volunteers, finding significant improvements in hair growth rate, hair density, scalp condition, and reduction in hair fall without notable adverse effects.

This research highlights advancements in reconstructive surgery for managing scars, emphasizing the importance of combined surgical and nonsurgical interventions like platelet-rich plasma and stem cell therapy to prevent and treat thick scar tissue while enhancing functionality and aesthetic outcomes.

This study identified that bone marrow-derived CD34⁺ cells act as fibroblast progenitors to enhance tissue regeneration in ischemic limbs by promoting angiogenesis through interactions with macrophages.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

This review discusses the use of stem cell therapies for hair diseases, highlighting promising results but reporting no new clinical findings.

This study found that primary stem cells from concentrated growth factor can differentiate into adipogenic, endothelial, and neuronal lineages in vitro, suggesting potential for use in regenerative therapies.

This review discusses the therapeutic potential of adipose-derived stem cells compared to other mesenchymal stem cells, emphasizing their promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, but reports no new clinical results.

This study suggests that human DSCCs may aid in hair follicle regeneration and reduce microinflammation, with potential applications in regenerative medicine evaluated through a new morphometric analysis.

Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.

This study found that exosomes from different mesenchymal stem cell sources had distinct effects on immune cell functions and varied microRNA expression profiles compared to their original cells.

This review highlights the potential of cell-free therapies, particularly cell extracts, in addressing radiation-induced salivary gland damage from head and neck cancer treatment, emphasizing their practicality and safety compared to traditional therapies despite incomplete understanding of their bioactive components.

This study found that an injectable calcium alginate-amelogenin hydrogel is biocompatible, degradable, anti-inflammatory, and promotes osteogenesis, which may enhance the bone healing process in jaw and facial bone defect areas by mediating the bone immune microenvironment.

In this study, patients receiving adipose-derived stromal vascular cell transplantation for alopecia areata experienced significant hair regeneration, increased growth, and improved hair quality after 3 and 6 months, indicating potential efficacy of this stem cell-based therapy for hair loss.