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Some horses lose hair without inflammation or itching due to various conditions, and while mainly a cosmetic issue, diagnosis requires examination and biopsies, and breeding is not advised if it's hereditary.

OCT can detect hidden hair follicles in alopecia areata, indicating potential hair regrowth.

Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.

Platelet-rich plasma treatment is not very effective for chronic severe alopecia areata.

Adding PRP to topical mometasone improves and speeds up alopecia areata treatment.

0.05% betamethasone dipropionate is the most effective treatment for mild alopecia areata.

Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.

Different botulinum toxin products and concentrations can effectively reduce sweating, itching, bladder pressure, hair loss, and muscle spasms.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Some African American women's central scalp hair loss is linked to genetics and past fungal scalp infections, with more research needed on other causes.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.